Results 41 to 50 of about 260,109 (261)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

How dietary patterns could have a role in prevention, progression, or management of diabetes mellitus? Review on the current evidence

open access: yesJournal of Research in Medical Sciences, 2012
Objective: To investigate the role of dietary patterns in prevention and management of type 2 diabetes mellitus. Materials and Methods: A systematic review of databases which were published in ISI, Cochrane Central Register of Controlled Trials databases,
Zahra Maghsoudi, Leila Azadbakht
doaj  

Healthy Aging and Dietary Patterns

open access: yesNutrients, 2022
A number of factors contribute to the complex process of aging, which finally define whether someone will or not develop age-associated chronic diseases in late life. These determinants comprise genetic susceptibility as well as various behavioral, environmental, and dietary factors, all of which have been shown to influence specific pathways ...
Dominguez, L. J.   +7 more
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Association between external eating and dietary patterns among middle school students in Chongqing, China

open access: yesFrontiers in Nutrition
BackgroundThe dietary pattern, serving as a comprehensive indicator of the nutritional intake of middle school students, plays a crucial role in guiding their health.
Yingjiao Deng   +28 more
doaj   +1 more source

Dietary patterns and cardiovascular disease [PDF]

open access: yesProceedings of the Nutrition Society, 2013
Despite strong prospective epidemiology and mechanistic evidence for the benefits of certain micronutrients in preventing CVD, neutral and negative outcomes from secondary intervention trials have undermined the efficacy of supplemental nutrition in preventing CVD.
C M, Williams   +2 more
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A social-ecological trap theory-informed investigation of dietary patterns in southwestern Madagascar

open access: yesFrontiers in Nutrition
BackgroundSocial-ecological trap theory highlights the potential for food systems and the social and environmental contexts within which they are situated to ‘trap’ individuals into a trajectory of specific nutritional outcomes when their physical or ...
Heather Kelahan   +16 more
doaj   +1 more source

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