Results 201 to 210 of about 270,810 (258)

The Certainty of the Evidence on Plant- vs Meat-Predominant Dietary Patterns and Depression: An Umbrella Review. [PDF]

Nutr Rev
Lee MF, Bayes J, Moustafa AA, Moustafa AA, Storz MA, Best T.   +5 more
europepmc   +1 more source

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source

Association of dietary patterns with mortality and life expectancy by frailty status: Evidence from the UK Biobank. [PDF]

J Nutr Health Aging
Kong W, Hu X, Zhang K, Zhang Y, Tian R, Peng Y, Chai L, Wang W, Zhang D, Fan J.   +9 more
europepmc   +1 more source

Melatonin Alleviates Graft Biliary Fibrosis by Inhibiting VIM+ Cholangiocyte Subcluster via Hypoxia/TGF‐β‐CREM‐VIM Axis

Advanced Science, EarlyView.
Single‐cell RNA sequencing verified the presence of the VIM+ biliary epithelial cell (BEC) in the bile ducts of NAS patients. The hypoxia/TGF‐β‐CREM‐VIM axis mediated phenotypic switch toward VIM+ BEC is validated using a hypoxia/TGF‐β‐stimulated cellular model, a rat liver transplantation model, BEC‐specific Crem conditional knockout rats, and BEC ...
Zhaoyi Wu, Nengsheng Fu, Zhongxin Huang, Yu Mou, Ensi Ma, Xiaoshi Wang, Tian Dong, Yujun Zhang, Danqing Liu, Di Jiang, Jingya Kuang, Rui Liao, Yifeng Tao, Leida Zhang, Chengcheng Zhang   +14 more
wiley   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source

Calibrated Dietary Patterns and Cancer Risk in the Women's Health Initiative Cohorts. [PDF]

Am J Epidemiol
Zhang X, Vasan S, Zheng C, Prentice RL, Navarro SL, Tinker L, Raftery D, Gowda GAN, Van Horn L, Sun Y, Tabung FK, Pan K, Lampe JW, Neuhouser ML.   +13 more
europepmc   +1 more source

Influence of Eating Behavior and Dietary Patterns on Gut Microbiota Formation in Children with Autism Spectrum Disorder. [PDF]

Nutrients
Smolko NA, Markelova MI, Synbulatova GE, Khusnutdinova DR, Sufianov AA, Sufianova GZ, Grigoryeva TV, Rizvanov AA, Faizullina RA, Mukhamedshina YO.   +9 more
europepmc   +1 more source

Maternal Dietary Patterns, Socioeconomic Conditions, and Birth Outcomes in the MAMI-MED and Piccolipiù Italian Birth Cohorts. [PDF]

Nutrients
Favara G, Leccese L, Barchitta M, Candelora F, Culasso M, Ettore C, Ettore G, Gagliardi L, Galvani F, Lastrucci V, La Mastra C, La Rosa MC, Magnano San Lio R, Maugeri A, Pani P, Nisticò L, Brescianini S, Agodi A.   +17 more
europepmc   +1 more source

Contrasting dietary patterns remodel gut microbial function and generate multi-omic signatures associated with cardiometabolic markers. [PDF]

Gut Microbes
Stanford J, Hoedt EC, Gómez-Martín M, Clarke ED, Duncanson K, Burrows T, Collins CE.   +6 more
europepmc   +1 more source