Results 31 to 40 of about 372,288 (257)

Rarely reported cases of hepatotoxicity associated with turmeric- and curcuminoid-containing dietary supplements: a comprehensive review by USP

open access: yesPharmaceutical Biology
Background The United States Pharmacopeia (USP) Dietary Supplement Admission Evaluation and Labeling Expert Committee (DSAEL EC) routinely monitors safety‑related literature for dietary ingredients covered by USP monographs. Following multiple reports of
Nadeem Akhtar   +8 more
doaj   +1 more source

Nutraceuticals in the Treatment of Major Depressive Disorder

open access: yesNutraceuticals
Major depressive disorder (MDD) is the most common mood disorder among adults. Despite the wide use of pharmacological agents by those with MDD, the evidence indicates that only a small fraction of patients benefits, and many individuals using ...
Allyson Davis   +2 more
doaj   +1 more source

Cinnamon-Derived Compounds Reduce PD-L1 Expression in UV-Exposed Human Skin Cell Line

open access: yesMedicines
Background/Objective: Ultraviolet A and B (UVAB) radiation is a major environmental factor that induces DNA damage and upregulates programmed death-ligand 1 (PD-L1) expression in skin cells, thereby contributing to immune evasion and impaired tissue ...
Chidambaram Ramanathan   +2 more
doaj   +1 more source

Vascepa protects against high-fat diet-induced glucose intolerance, insulin resistance, and impaired β-cell function

open access: yesiScience, 2021
Summary: Omega-3 fatty acid prescription drugs, Vascepa (≥96% eicosapentaenoic acid [EPA] ethyl ester) and Lovaza (46.5% EPA and 37.5% docosahexaenoic acid ethyl ester) are known therapeutic regimens to treat hypertriglyceridemia.
Dana Al Rijjal   +10 more
doaj   +1 more source

Prevalence, patterns, and attitude regarding dietary supplement use in Saudi Arabia: Data from 2019.

open access: yesPLoS ONE, 2022
Dietary supplements are products containing dietary elements including vitamins, minerals, amino acids, herbs, or botanicals. They can aid consumers with low dietary intake and quality, as well as those with high demands, by boosting nutritious value.
Anwar M Alhashem   +6 more
doaj   +2 more sources

Development of an elective course on dietary supplements for undergraduate college students

open access: yesCogent Public Health
Due to little dietary supplement regulation and misinformation online, there is a need to educate consumers on them, which could be addressed using a higher education course to provide students resources to evaluate supplement information.
Tyler B. Becker   +2 more
doaj   +1 more source

Dietary Supplement Use in Transmasculine Spectrum Populations

open access: yes, 2022
Introduction: There are currently no dietary guidelines for the transgender community, and very little is known about the specific nutritional needs of this population.
Kalman-Rome, Eli
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Vitamin D supplementation therapy – comparison of efficacy of three different protocols [PDF]

open access: yesJournal of Clinical and Scientific Research, 2015
Background: To study the efficacy of vitamin D supplementation therapy with three different protocols. Methods: In protocols 1 (intensive) and 3 (standard) oral cholecalciferol was given 60,000 IU/week/8 weeks followed bimonthly for 12 weeks.
Harinarayan CV   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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