Results 181 to 190 of about 37,112 (220)

Effects of Bisphenol A, Diethylhexyl Phthalate, and Pentabrominated Diphenyl Ether 99 on Steroid Synthesis in Cultured Bovine Luteal Cells.

Reproduction in domestic animals = Zuchthygiene, 2020
Bisphenol A (BPA), diethylhexyl phthalate (DEHP), and pentabrominated diphenyl ether 99 (PBDE 99) are environmental toxicants belonging to the endocrine disrupting compounds (EDCs).
R. Kabakçı, A. Yi̇ği̇t
semanticscholar   +1 more source

Transgenerational inheritance of ovarian development deficiency induced by maternal diethylhexyl phthalate exposure

Reproduction, Fertility and Development, 2014
Diethylhexyl phthalate (DEHP) is a widely used industrial additive for increasing plastic flexibility. It disrupts the physiological functions of endogenous hormones and induces abnormal development of mammals. The objectives of the present study were to evaluate the effects of DEHP exposure on ovarian development of pregnant mice and whether the ...
Xi-Feng, Zhang, Teng, Zhang, Zhe, Han, Jing-Cai, Liu, Yu-Ping, Liu, Jun-Yu, Ma, Lan, Li, Wei, Shen   +7 more
openaire   +2 more sources

Diethylhexyl phthalate as a factor in blood tranfusion and haemodialysis

Toxicology, 1978
Di-2-ethylhexyl phthalate (DEHP), the most frequently occurring plasticiser in medical equipment manufactured from polymers of vinyl chloride, forms about 40% w/w of tubes and containers used for storing blood and for haemodialysis. The plasticiser leaches out into liquids with lipid contents, although it is very sparingly soluble in purely aqueous ...
openaire   +2 more sources

Leaching of diethylhexyl phthalate from polyvinyl chloride bags into intravenous etoposide solution

Journal of Clinical Pharmacy and Therapeutics, 2002
To compare the release of diethylhexyl phthalate (DEHP) from polyvinyl chloride (PVC) bags from four different manufacturers into intravenous etoposide solutions.Etoposide solutions, 0.4 mg/mL, containing the vehicle polysorbate 80 were prepared in 5% dextrose or 0.9% sodium chloride injection PVC bags and stored at room temperature for 24 h.
B, Demoré, J, Vigneron, A, Perrin, M A, Hoffman, M, Hoffman   +4 more
openaire   +2 more sources

Diethylhexyl phthalate impairs insulin binding and glucose oxidation in Chang liver cells

Toxicology in Vitro, 2007
The present study examined the dose-dependent effects of diethylhexyl phthalate (DEHP) on insulin receptor concentration and glucose oxidation in Chang liver cells. Chang liver cells (5 x 10(5) cells) were exposed to different concentrations (0, 50, 100, 200 and 400 microM) of DEHP for 24h.
Srinivasan, Rengarajan, Chandrakesan, Parthasarathy, Malat, Anitha, Karundevi, Balasubramanian   +3 more
openaire   +2 more sources

Five‐day storage of platelets in a non‐diethylhexyl phthalate‐plasticized container

Transfusion, 1992
A non‐diethylhexyl phthalate (DEHP)‐plasticized blood bag for 5‐day storage of random‐donor platelet concentrates has been developed. The plastic bag is composed of polyvinylchloride plastic with a butyryl trihexyl citrate plasticizer. The suitability of this plastic for the storage of platelet concentrates for use in clinical transfusion practice was ...
E L, Snyder, R H, Aster, A, Heaton, G, Grode, P, Napychank, L, Kagen, L C, Jefferies, S, Hedberg, D H, Buchholz   +8 more
openaire   +2 more sources

Leaching of diethylhexyl phthalate from polyvinyl chloride bags into intravenous cyclosporine solution

American Journal of Health-System Pharmacy, 1986
The release of diethylhexyl phthalate (DEHP) from flexible polyvinyl chloride containers into intravenous cyclosporine solutions was studied. Intravenous cyclosporine solution or solutions containing the vehicle Cremophor EL and alcohol in dextrose were prepared in an all-glass system and stored in polyvinyl chloride (PVC) bags.
R, Venkataramanan, G J, Burckart, R J, Ptachcinski, R, Blaha, L W, Logue, A, Bahnson, C S, Giam, J E, Brady   +7 more
openaire   +2 more sources

Leaching of diethylhexyl phthalate from polyvinyl chloride materials into etoposide intravenous solutions

Journal of Oncology Pharmacy Practice, 2005
Etoposide intravenous solution is associated with leaching of diethylhexyl phthalate (DEHP) from bags and tubings made from polyvinyl chloride (PVC). Recent evidence suggests that this may be more substantial than previously found. Since DEHP is potentially hepatotoxic and carcinogenic, it is preferable to prepare and administer etopo-side bags and ...
Mário L, de Lemos, Linda, Hamata, Thanh, Vu   +2 more
openaire   +2 more sources

Leaching of diethylhexyl phthalate from PVC bags into intravenous teniposide solution

International Journal of Pharmaceutics, 1994
Abstract The stability of teniposide in various diluents and polyvinyl chloride bags was determined, and the extent of leaching of di(2-ethylhexyl) phthalate (DEHP) from PVC bags caused by the teniposide formulation was measured. No significant drug loss was observed during simulated infusions ( n = 4) for 1 h using PVC infusion bags and ...
M FAOUZI, T DINE, M LUYCKX, B GRESSIER, F GOUDALIEZ, M MALLEVAIS, C BRUNET, M CAZIN, J CAZIN   +8 more
openaire   +1 more source

Mechanisms underlying the anti-androgenic effects of diethylhexyl phthalate in fetal rat testis

Toxicology, 2006
Diethylhexyl phthalate (DEHP) is widely used as a plasticizer in consumer products and is known to disturb the development of the male reproductive system in rats. The mechanisms by which DEHP exerts these effects are not yet fully elucidated, though some of the effects are related to reduced fetal testosterone production.
Julie, Borch, Stine Broeng, Metzdorff, Anne Marie, Vinggaard, Leon, Brokken, Majken, Dalgaard   +4 more
openaire   +2 more sources