Analysis of Latife Tekin's novels in the context of Kristeva's Semiotic Chora and Derrida's Différance concepts [PDF]
Latife Tekin'in romanları, semiyotik ve sembolik düzenlerin iç içe geçtiği, dilin sınırlarının zorlandığı çok katmanlı bir edebi yapı sunar. Bu çalışmada, Latife Tekin'in romanlarındaki dil; Julia Kristeva'nın semiyotik khora, Jacques Derrida'nın ...
Ağırbay, Fatma
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Two Attitudes towards Textuality in International Law: The Battle for Dualism. [PDF]
Oxf J Leg Stud, 2022 d'Aspremont J.
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Care for Language: Etymology as a Continental Argument in Bioethics. [PDF]
J Bioeth Inq, 2021 Zwart H.
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Derridian différance. Is a Spelling Mistake Translatable?
, 2015 The article examines Polish translations of the Derridian term différance. Polish philosophical discourse uses the following renditions of différance: róż(ni(c) oś)ć by Bogdan Banasiak, różNICa by Tadeusz Sławek, gra-na-zwłokę-o-różnicę by Stanisław ...
Marzec, Andrzej
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Deconstrucción y teología negativa. El juego entre différance y diferencia ontológica
Estudios de Filosofía, 2014 Pese a las recurrentes advertencias de Derrida acerca de no pasar por alto la frontera que separa la deconstrucción de la teología negativa, malentendido que, según él, desvirtuaría el radical alcance crítico pretendido por la primera, su intento por ...
Diana María Muñoz González
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source