Results 81 to 90 of about 2,344 (223)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Jorie Graham’s Overlord: Poetics, Ethics, and Différance
, 2014 English Department Honors Thesis.*Overlord* by Jorie Graham requires a theoretical paradigm which can account for the Overlord within it; this paradigm, I will argue, is Jacques Derrida’s différance.
Stevens, Jeremy
core
Music in the Thought of Deconstruction / Deconstruction in the Thought of Music (For Joseph Dubiel)
Muzikološki Zbornik, 2005 This article critically speculates on points of affinity and difference between, on the one hand, musicological writings and the musical practices they attempt to represent and, on the other, the operation of deconstruction (defined in terms of the ...
Martin Scherzinger
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Enjeux de la différance chez Jacques Derrida
, 2003 La thèse comprend deux parties, qui visent à vérifier deux hypothèses principales.La première consiste à se demander si la déconstruction derridienne de la métaphysique traditionnelle ne joue pas, au su ou à l’insu de Derrida, un double rôle :d’une part,
Okitadjonga Anyikoy Wa Anyikoy, Gaspard
core
Muzikološki Zbornik, 2005 Entirely dissimilar endeavours of problematizing a canonic positioning of music, musicology, aesthetics and philosophy through self-comprehensiveness of a piece-as-a-source hoe et tunc, have led to criticism ar deconstruction of 'self-comprehensiveness ...
Miško Šuvaković
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Reading Under Observation: délire Lolita
Sillages Critiques, 2010 This article aims at, if not answering, at least raising the question: What is it exactly that we read when we read Lolita? If Vladimir Nabokov’s narrator overtly plays with his readers, he too, whether he knows it or not, is being toyed with.
Stéphane Vanderhaeghe
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source