The efficacy and safety of intraocular anti-VEGF injections versus anti-VEGF combined with steroids or steroid monotherapy for macular edema secondary to retinal vein occlusion: a systematic review and meta-analysis of randomized controlled trials. [PDF]
Front Med (Lausanne)Cai H, Tian M, Huang Z, Wang B.
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
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The effect of orthotic treatment on plantar pressure distribution in patients with adolescent idiopathic scoliosis: A prospective observational study. [PDF]
Medicine (Baltimore)Liu W +8 more
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
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Dynamic coupling effects of geometric eccentricity on multi-stage gear transmission via stiffness modulation and error excitation. [PDF]
Sci RepLu W, Liang G, Du Z, Huang W, Zhao X.
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Unsupervised Variational-Autoencoder-Based Analysis of Morphological Representations in Magnetic-Nanoparticle-Treated Macrophages. [PDF]
Bioengineering (Basel)Hwang SY +5 more
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A Wearable Ultrasound Sensing System for Soft Tissue Stiffness Detection: A Feasibility Study. [PDF]
Biosensors (Basel)Bao G, Xu T, Li X, Meng B.
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