Results 131 to 140 of about 440,924 (308)

Solvability of a one-parameter class of nonlinear second-order difference equations by invariants

, 2019
By using an invariant we show in an original and quite unexpected way that a one-parameter class of nonlinear second-order difference equations is solvable in closed form, improving and theoretically explaining a recent result in the literature.
Stevo Stević
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Unification of integrable q-difference equations

Electronic Journal of Differential Equations, 2015
This article presents a unifying framework for q-discrete equations. We introduce a generalized q-difference equation in Hirota bilinear form and develop the associated three-q-soliton solutions which are described in polynomials of power functions ...
Burcu Silindir, Duygu Soyoglu
doaj  

Functional difference equations and eigenfunctions of a Schrödinger operator with δ' -interaction on a circular conical surface. [PDF]

Proc Math Phys Eng Sci, 2020
Lyalinov MA.
europepmc   +1 more source

A family of difference schemes for fourth order parabolic partial differential equations

, 1983
A family of methods is developed for the numerical solution of fourth order parabolic partial differential equations in one- and two-space variables.
Khaliq, AQM, Twizell, EH
core  

Existence Results and Finite-Time Stability of a Fractional (p,q)-Integro-Difference System [PDF]

In this article, we mainly generalize the results in the literature for a fractional q-difference equation. Our study considers a more comprehensive type of fractional p,q-difference system of nonlinear equations.
Amir Abdel Menaem, Mesmouli, M. B., Hassan, T. S., Abdel, Menaem, A., Taher S. Hassan, Loredana Florentina Iambor, Mouataz Billah Mesmouli, Iambor, L. F.   +7 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Andronov-Hopf and Neimark-Sacker bifurcations in time-delay differential equations and difference equations with applications to models for diseases and animal populations. [PDF]

Adv Differ Equ, 2020
Darlai R, Moore EJ, Koonprasert S.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source