The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Existence of zero-order meromorphic solutions of certain q-difference equations. [PDF]
J Inequal Appl, 2018 Du Y, Gao Z, Zhang J, Zhao M.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Stability of Difference Equations with Interspecific Density Dependence, Competition, and Maturation Delays. [PDF]
Bull Math BiolHosack GR, El-Hachem M, Beeton NJ.
europepmc +1 more source
Boundedness, persistence and stability for classes of forced difference equations arising in population ecology. [PDF]
J Math Biol, 2019 Franco D +3 more
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Anti-periodic boundary value problem for first order impulsive delay difference equations
, 2015 Peiguang Wang, Wenli Wang
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Corrigendum to "Numerical investigation of singularly perturbed time lag parabolic differential-difference equations" [Heliyon Volume 11, Issue 1, January 2025, Article e41215]. [PDF]
HeliyonDaba IT, Melesse WG, Gelu FW, Kebede GD.
europepmc +1 more source
Oscillations in deviating difference equations using an iterative technique. [PDF]
J Inequal Appl, 2017 Chatzarakis GE, Jadlovská I.
europepmc +1 more source