Results 51 to 60 of about 440,924 (308)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Qualitative Behavior of the Solutions to Delay and Difference Equations

open access: yesВестник КазНУ. Серия математика, механика, информатика, 2018
It is noteworthy to observe that a first-order linear ordinary differential equation without delay does not possess oscillatory solutions. Therefore the investigation of oscillatory solutions is of interest for equations with delays or for the discrete
P. Ioannis
doaj   +1 more source

Well-posedness of delay parabolic difference equations [PDF]

open access: yes, 2014
The well-posedness of difference schemes of the initial value problem for delay differential equations with unbounded operators acting on delay terms in an arbitrary Banach space is studied.
Allaberen Ashyralyev   +3 more
core   +1 more source

Dirichlet and Neumann Boundary Value Problems for Dunkl Polyharmonic Equations

open access: yes, 2023
Dunkl operators are a family of commuting differential–difference operators associated with a finite reflection group. These operators play a key role in the area of harmonic analysis and theory of spherical functions.
Valery Karachik, Hongfen Yuan
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Investigation of linear difference equations with random effects

open access: yes, 2020
In this study, random linear difference equations obtained by transforming the components of deterministic difference equations to random variables are investigated.
Merdan, Mehmet, Sisman, Seyma
core   +1 more source

Difference Equations Everywhere : Some Motivating Examples [PDF]

open access: yes, 2019
Publicació amb motiu de la International Conference on Difference Equations and Applications (July 24-28, 2017, Timişoara, Romania) amb el títol Difference Equations, Discrete Dynamical Systems and ApplicationsThis work collects several situations where ...
Gasull, Armengol
core   +1 more source

On a class of difference equations with interlacing indices

open access: yes, 2021
Some results on the long-term behavior of solutions to a class of difference equations, which includes numerous nonlinear difference equations of various orders that attracted some attention in the last 15 years, are presented.
Stevič, Stevo   +7 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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