Results 71 to 80 of about 4,636,999 (250)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Inverse-Positive Matrices and Stability Properties of Linear Stochastic Difference Equations with Aftereffect

open access: yes
This article examines the stability properties of linear stochastic difference equations with delays. For this purpose, a novel approach is used that combines the theory of inverse-positive matrices and the asymptotic methods developed by N.V.
Kadiev, Ramazan I.   +3 more
core   +1 more source

Finite-difference solutions of tenth-order boundary-value problems [PDF]

open access: yes, 1994
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.In this thesis finite difference methods are used to obtain numerical solutions for a class of high-order ordinary differential equations with applications ...
Siddiqui, Aijaz Ahmad
core   +5 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

On the solvability of initial-value problems for nonlinear implicit difference equations [PDF]

open access: yes, 2004
Our aim is twofold. First, we propose a natural definition of index for linear nonautonomous implicit difference equations, which is similar to that of linear differential-algebraic equations.
Pham Ky Anh   +3 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

On the Nonlocal Fractional Delta-Nabla Sum Boundary Value Problem for Sequential Fractional Delta-Nabla Sum-Difference Equations

open access: yes, 2020
In this paper, we propose sequential fractional delta-nabla sum-difference equations with nonlocal fractional delta-nabla sum boundary conditions.
Jiraporn Reunsumrit   +1 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Difference equations over fields of elliptic functions.

open access: yes, 2021
Adamczewski and Bell proved in 2017 a 30-year old conjecture of Loxton and van der Poorten, asserting that a Laurent power series, which simultaneously satisfies a p-Mahler equation and a q-Mahler equation for multiplicatively independent integers p and ...
Deshalit, Ehud
core   +1 more source

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