Results 131 to 140 of about 579,279 (262)

Relationship between the efficacy of micro-implant-assisted rapid maxillary arch expansion and maturation of the midpalatal sutures. [PDF]

Acta Odontol Scand
Li S, Tian J, Li Y, Song W.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Three-Dimensional Radiographic and Morphological Features of Ameloblastoma and Odontogenic Keratocyst: A Comparative Cone Beam Computed Tomography Study Using Automatic Segmentation. [PDF]

Int Dent J
Li L, Huang S, Zhang X, Liu X, Cheng Y, Yang K, Zhang L, He H, Huang Z.   +8 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Gender differences in understanding of thermal expansion

Glasnik hemičara i tehnologa Bosne i Hercegovine = Bulletin of the Chemists and Technologists of Bosnia and Herzegovina, 2018
Investigation of gender differences in science allows us to tailor our instruction to the needs, interests and abilities of all our students. In this study we aimed to investigate gender differences in conceptual understanding of thermal expansion.
openaire   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Association of medicaid expansion with lung cancer-specific and overall mortality: A difference-in-differences analysis. [PDF]

PLoS One
Akinyemi O, Fasokun M, Eze A, Ugochukwu N, Arshad S, Belie O, Hughes K, Cornwell Iii E, Levy G.   +8 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Extrusion Processing and Formulation Effects on the Techno-Functional Properties of Melon Peel-Enriched Soy Protein-Maize Starch Snacks. [PDF]

Int J Food Sci
Hernández-Santos B, Rodríguez-Miranda J, Herman-Lara E, Ramírez-Rivera EJ, Torruco-Uco JG, Juárez-Barrientos JM, Rivadeneyra-Rodríguez JM, Ángeles-Hernández A, Ramírez-Figueroa E.   +8 more
europepmc   +1 more source