Results 61 to 70 of about 1,263,858 (270)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

COMPARING DIFFERENT SCHEMES FOR RANDOM ARRAYS

open access: yesProgress In Electromagnetics Research B, 2016
In this work, four types of random arrays are compared. In particular, the mean and variance of the array factor are derived. This provides a partial statistical characterisation that allows pointing out some important aspects of random arrays and link them to the number of elements and array aperture.
Buonanno Giovanni, Solimene Raffaele
openaire   +2 more sources

SIMULATION OF MULTIPHASE FLOWS IN THE SUBSURFACE ON SUPERCOMPUTERS WITH THE USE OF EXPLICIT DIFFERENCE SCHEMES [PDF]

open access: bronze, 2018
B.N. Chetvertushkin   +3 more
openalex   +1 more source

Application of Fuzzy Finite Difference Scheme for the Non-homogeneous Fuzzy Heat Equation [PDF]

open access: green, 2021
Samaneh Zabihi   +3 more
openalex   +1 more source

Comparison of finite-difference schemes for analysis of shells of revolution [PDF]

open access: yes
Several finite difference schemes are applied to the stress and free vibration analysis of homogeneous isotropic and layered orthotropic shells of revolution.
Noor, A. K., Stephens, W. B.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Convenient total variation diminishing conditions for nonlinear difference schemes [PDF]

open access: yes
Convenient conditions for nonlinear difference schemes to be total-variation diminishing (TVD) are reviewed. It is shown that such schemes share the TVD property, provided their numerical fluxes meet a certain positivity condition at extrema values but ...
Tadmor, Eitan
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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