Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Insight into the Dynamics of Fractional Maxwell Nano-Fluids Subject to Entropy Generation, Lorentz Force and Heat Source via Finite Difference Scheme [PDF]
Muhammad Imran Asjad +4 more
openalex +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
COMPARING DIFFERENT SCHEMES FOR RANDOM ARRAYS
In this work, four types of random arrays are compared. In particular, the mean and variance of the array factor are derived. This provides a partial statistical characterisation that allows pointing out some important aspects of random arrays and link them to the number of elements and array aperture.
Buonanno Giovanni, Solimene Raffaele
openaire +2 more sources
SIMULATION OF MULTIPHASE FLOWS IN THE SUBSURFACE ON SUPERCOMPUTERS WITH THE USE OF EXPLICIT DIFFERENCE SCHEMES [PDF]
B.N. Chetvertushkin +3 more
openalex +1 more source
Application of Fuzzy Finite Difference Scheme for the Non-homogeneous Fuzzy Heat Equation [PDF]
Samaneh Zabihi +3 more
openalex +1 more source
Comparison of finite-difference schemes for analysis of shells of revolution [PDF]
Several finite difference schemes are applied to the stress and free vibration analysis of homogeneous isotropic and layered orthotropic shells of revolution.
Noor, A. K., Stephens, W. B.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Convenient total variation diminishing conditions for nonlinear difference schemes [PDF]
Convenient conditions for nonlinear difference schemes to be total-variation diminishing (TVD) are reviewed. It is shown that such schemes share the TVD property, provided their numerical fluxes meet a certain positivity condition at extrema values but ...
Tadmor, Eitan
core +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source

