Results 81 to 90 of about 2,431,645 (337)

A Pilot Survey of Indian Stakeholders: Parents, Doctors, and Grown-Up Patients of Disorders of Sexual Differentiation on Management Decisions and Associated Gender Dysphoria

Journal of Indian Association of Pediatric Surgeons
Background and Aims: Of late, there are many legal representations from select quarters to halt all medical interventions in children with differences of sex development (DSD).
Simmi K. Ratan, Sujoy Neogi, Md Fahim Ahmad, Kanishka Das, Vijaya Raman, Pradnya S. Bendre, Arka Banerjee, Shilpa Sharma, Himanshu Acharya, Vikesh Agrawal, Ramesh Babu   +10 more
doaj   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

SRY+ Derivative X Chromosome in a Female With Apparently Typical Sexual Development

Molecular Genetics & Genomic Medicine
Background When the SRY gene is present in a 46,XX fetus, some degree of testicular development is expected. Our laboratory performed prenatal genetic testing for a fetus that had screened positive for Y chromosome material by noninvasive prenatal ...
Casey J. Brewer, Alyxis G. Coyan, Nicki Smith, Brittany Jones, Teresa A. Smolarek, Jie Liu   +5 more
doaj   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Laparoscopy versus ultrasonography for the evaluation of Müllerian duct remnants in male patients with disorder of sex differentiation

Egyptian Pediatric Association Gazette
Background The diagnosis of male differences of sex development is a challenging multidisciplinary team task, that requires external genital evaluation, karyotyping, hormonal profiling, radiological work up and frequently diagnostic laparoscopy and ...
Mohamed Sayed Abd El-Monsif, Noha Arafa, Mahmoud Marei Marei, Gamal Eltagy, Ahmed M. K. Wishahy   +4 more
doaj   +1 more source

Decisional support needed when facing tough decisions: Survey of parents with children having differences of sex development [PDF]

, 2023
Melissa Gardner, William B. Brinkman, Meg Carley, Noi Liang, Sophie Lightfoot, Kendra Pinkelman, Phyllis Speiser, Tara Schafer-Kalkhoff, Kristina I. Suorsa-Johnson, Brian A. VanderBrink, Erica M. Weidler, Jessica Wisniewski, Dawn Stacey, David E. Sandberg   +13 more
openalex   +1 more source

Violence indicators in Quebrada de Humahuaca, Jujuy, Argentina: The Regional Development Period from a regional perspective [PDF]

, 2014
Quebrada de Humahuaca (Jujuy, Argentina) has been extensively studied by archaeologists. Studies have been focused mainly on the Late Regional Development Period (1250 1430 AD), which has been defined as a time of social conflict.
Botta, Florencia Natalia, Seldes, Verónica   +1 more
core   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Genetic variants (Lhcgr W495X/+) and environmental toxicants (DEHP) synergistically induce DSD by interfering with steroidogenic gene expression

Biology of Sex Differences
Background Emerging evidence suggests that genetic variants and environmental toxicants may synergistically contribute to DSD. To test this hypothesis, we employed Lhcgr W495X/+ (luteinizing hormone/chorionic gonadotropin receptor) male mice subjected to
Xie Qigen, Xia Kai, Cao Haiming, Xu Zhe, Gao Yong, Deng Chunhua   +5 more
doaj   +1 more source