Results 171 to 180 of about 1,832,263 (342)
Expression profile of rice PLC gene family during developmental stages.
, 2013 Average signal intensity (GCRMA) value of three replicates from microarray for all the developmental stages (three vegetative; L-mature leaf, R-root, SDL-seven day old seedling, six panicle stages; P1–P6 and five seed stages; S1–S5) has been plotted to ...
Poonam Kanwar (182649) +6 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Subjective meaning of time in different developmental stages [PDF]
, 2014 The topic of the thesis is subjective perception of time in different developmental stages. In the theoretical part the concept of time is defined from different perspectives. We already know a lot about time from the scientific perspective, but the main
Papić, Ina
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Revista Científica, 2010 Descriptions of the different imrnature stages (redia, cercaria, and metacercaria) and adult stage of Centrocestus formosanus (Nishigori) are presented. Between 32 and 36 circumoral spines are generally reported for the C.
Luz Elena Hernández +2 more
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Expression of Two Survivin Variants in Different Developmental Stages of Mouse Ovaries
پزشکی بالینی ابن سینا, 2009 Introduction & Objective: Survivin is one of the new characterized members of the inhibitor of apoptosis proteins that shows widespread expression in embryonic and tumoric tissues. The aim of this study was to evaluate the expression of Survivin variants
Tahereh Mazoochi +2 more
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source