Results 1 to 10 of about 253,829 (285)
mSystems, 2017 Archetypal pathogenic bacterial strains are often used to elucidate regulatory networks of an entire pathovar, which encompasses multiple lineages and phylogroups. With enteropathogenic Escherichia coli (EPEC) as a model system, Hazen and colleagues (mSystems 6:e00024-17, 2017, https://doi.org/10.1128 ...
Amy Platenkamp, Jay L. Mellies
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A practical, bioinformatic workflow system for large data sets generated by next-generation sequencing [PDF]
, 2010 Transcriptomics (at the level of single cells, tissues and/or whole organisms) underpins many fields of biomedical science, from understanding the basic cellular function in model organisms, to the elucidation of the biological events that govern the ...
Aaron R. Jex +95 more
core +11 more sources
Improving ancient DNA genome assembly [PDF]
PeerJ, 2017 Most reconstruction methods for genomes of ancient origin that are used today require a closely related reference. In order to identify genomic rearrangements or the deletion of whole genes, de novo assembly has to be used.
Alexander Seitz, Kay Nieselt
doaj +2 more sources
Archaea, 2010 DNA microarray technology allows for a quick and easy comparison of complete transcriptomes, resulting in improved molecular insight in fluctuations of gene expression. After emergence of the microarray technology about a decade ago, the technique has now matured and has become routine in many molecular biology laboratories.
Walther, J. +2 more
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Identification and characterization of a novel enhancer in the HTLV-1 proviral genome
Nature Communications, 2022 Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic virus with constantly active antisense transcription from the proviral genome. Here, Matsuo et al.
Misaki Matsuo +16 more
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HTLV-1 persistence and leukemogenesis: A game of hide-and-seek with the host immune system
Frontiers in Immunology, 2022 Human T-cell leukemia virus type 1 (HTLV-1), a retrovirus which mainly infects CD4+ T cells and causes adult T-cell leukemia/lymphoma (ATL), is primarily transmitted via direct cell-to-cell transmission.
Benjy J. Y. Tan +3 more
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High-depth spatial transcriptome analysis by photo-isolation chemistry
Nature Communications, 2021 Spatial analysis of RNAseq data is important. Here the authors report a method for transcriptome profiling combined with photo-isolation chemistry to allow determination of expression profiles specifically from photo-irradiated regions of interest which ...
Mizuki Honda +7 more
doaj +1 more source
Cells, 2022 Background: Glioblastoma (GB) is a devastating primary brain malignancy. The recurrence of GB is inevitable despite the standard treatment of surgery, chemotherapy, and radiation, and the median survival is limited to around 15 months.
Francesca Lessi +10 more
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BMC Cancer, 2019 Background Central nervous system lymphomas (CNSL) is a devastating disease. Currently, a confirmatory biopsy is required prior to treatment. Objective Our investigation aims to prove the feasibility of a minimally-invasive diagnostic approach for the ...
Anne-Katrin Hickmann +7 more
doaj +1 more source
Nutrigenomics and immune function in fish : new insights from omics technologies [PDF]
, 2017 This study was funded by BBSRC grant BB/M026604/1.Peer reviewedPublisher ...
Krol, Elzbieta, Martin, Samuel A. M.
core +1 more source