Results 11 to 20 of about 156,189 (261)
mSystems, 2017 Archetypal pathogenic bacterial strains are often used to elucidate regulatory networks of an entire pathovar, which encompasses multiple lineages and phylogroups. With enteropathogenic Escherichia coli (EPEC) as a model system, Hazen and colleagues (mSystems 6:e00024-17, 2017, https://doi.org/10.1128 ...
Amy Platenkamp, Jay L. Mellies
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Transcriptomics in ecotoxicology [PDF]
Analytical and Bioanalytical Chemistry, 2010 The emergence of analytical tools for high-throughput screening of biomolecules has revolutionized the way in which toxicologists explore the impact of chemicals or other stressors on organisms. One of the most developed and routinely applied high-throughput analysis approaches is transcriptomics, also often referred to as gene expression profiling ...
Schirmer, Kristin +3 more
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Museum of Spatial Transcriptomics [PDF]
Nature Methods, 2020 Abstract The function of many biological systems, such as embryos, liver lobules, intestinal villi, and tumors depends on the spatial organization of their cells. In the past decade high-throughput technologies have been developed to quantify gene expression in space, and computational methods have been developed that
Lambda Moses, Lior Pachter
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Archaea, 2010 DNA microarray technology allows for a quick and easy comparison of complete transcriptomes, resulting in improved molecular insight in fluctuations of gene expression. After emergence of the microarray technology about a decade ago, the technique has now matured and has become routine in many molecular biology laboratories.
Walther, J. +2 more
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Oomycete transcriptomics database: A resource for oomycete transcriptomes [PDF]
BMC Genomics, 2012 Oomycete pathogens have attracted significant attention in recent years due to their economic impact. With improving sequencing technologies, large amounts of oomycete transcriptomics data are now available which have great biological utility. A known bottleneck with next generation sequencing data however lies with their analysis, interpretation ...
Tripathy Sucheta +2 more
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Microbiome, 2018 Background The expected increase in global surface temperature due to climate change may have a tremendous effect on the structure and function of the anaerobic food web in flooded rice field soil.
Jingjing Peng +4 more
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Transcriptomics in toxicology [PDF]
Food and Chemical Toxicology, 2017 Xenobiotics, of which many are toxic, may enter the human body through multiple routes. Excessive human exposure to xenobiotics may exceed the body's capacity to defend against the xenobiotic-induced toxicity and result in potentially fatal adverse health effects.
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Modeling population size independent tissue epigenomes by ChIL‐seq with single thin sections
Molecular Systems Biology, 2021 Recent advances in genome‐wide technologies have enabled analyses using small cell numbers of even single cells. However, obtaining tissue epigenomes with cell‐type resolution from large organs and tissues still remains challenging, especially when the ...
Kazumitsu Maehara +11 more
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STAR Protocols, 2022 Summary: Photo-isolation chemistry (PIC) enables isolation of transcriptome information from locally defined areas by photo-irradiation. Here, we present an optimized PIC protocol for formalin-fixed frozen and paraffin mouse sections and fresh-frozen ...
Mizuki Honda +6 more
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