Results 11 to 20 of about 213,758 (264)

The dawn of spatiotemporal transcriptomics

Biomedical Analysis
Gene expression of cells in the tissues is a heterogeneous and dynamic program across space and time. Spatiotemporal transcriptomics technologies have emerged as transforming tools to dissect the spatiotemporal patterns of gene regulation in diverse ...
Siying Wang, Shichao Lin, Chaoyong Yang
doaj   +2 more sources

Spatial Transcriptomics: Emerging Technologies in Tissue Gene Expression Profiling [PDF]

, 2023
Spatial transcriptomics technologies are providing new insights to study gene expression, allowing researchers to investigate the spatial organization of transcriptomes in cells and tissues.
Rosario M., Sanchez-Martin, Juan J., Diaz-Mochon*, Agustín, Robles-Remacho*   +2 more
core   +1 more source

Introduction to Transcriptomics

, 2021
Slide deck for a presentation on transcriptomics, delivered on 25.06.2021 during a training session entitled 'Beginner's Guide to Bioinformatics,' organized by Helix Biogen Institute in ...
Ahmad, Umar
core   +1 more source

ScialdoneLab/Spatial-Transcriptomics: mouse3Dnose

, 2022
This release contains the scripts used for the analysis presented in the article "A 3D transcriptomics atlas of the mouse nose sheds light into the anatomical logic of smell", as well as the code for the shiny app for 3D visualisation of gene expression ...
Mayra L. Ruiz Tejada Segura
core   +1 more source

Imaging-transcriptomics: python package

, 2021
First release of the imaging transcriptomics ...
Daniel Martins, Alessio Giacomel
core   +1 more source

Transcriptomics-Guided In Silico Drug Repurposing: Identifying New Candidates with Dual-Stage Antiplasmodial Activity

, 2023
In tropical and subtropical areas, malaria stands as a profound public health challenge, causing an estimated 247 million cases worldwide annually. Given the absence of a viable vaccine, the timely and effective treatment of malaria remains a critical ...
Carolina Horta Andrade (2820991), Fabio T. M. Costa (7380083), Larissa A. Ferreira (7141727), Aline Rimoldi (16921012), Luís C. Salazar Alvarez (16921015), Daniel Y. Bargieri (4912819), Joyce V. B. Borba (9211146), Juliana Calit (4912816), Beatriz Rosa de Azevedo (16921009)   +8 more
core   +2 more sources

Metatranscriptomics reveals a differential temperature effect on the structural and functional organization of the anaerobic food web in rice field soil

Microbiome, 2018
Background The expected increase in global surface temperature due to climate change may have a tremendous effect on the structure and function of the anaerobic food web in flooded rice field soil.
Jingjing Peng, Carl-Eric Wegner, Qicheng Bei, Pengfei Liu, Werner Liesack   +4 more
doaj   +1 more source

Photo-isolation chemistry for high-resolution and deep spatial transcriptome with mouse tissue sections

STAR Protocols, 2022
Summary: Photo-isolation chemistry (PIC) enables isolation of transcriptome information from locally defined areas by photo-irradiation. Here, we present an optimized PIC protocol for formalin-fixed frozen and paraffin mouse sections and fresh-frozen ...
Mizuki Honda, Ryuichi Kimura, Akihito Harada, Kazumitsu Maehara, Kaori Tanaka, Yasuyuki Ohkawa, Shinya Oki   +6 more
doaj   +1 more source

Modeling population size independent tissue epigenomes by ChIL‐seq with single thin sections

Molecular Systems Biology, 2021
Recent advances in genome‐wide technologies have enabled analyses using small cell numbers of even single cells. However, obtaining tissue epigenomes with cell‐type resolution from large organs and tissues still remains challenging, especially when the ...
Kazumitsu Maehara, Kosuke Tomimatsu, Akihito Harada, Kaori Tanaka, Shoko Sato, Megumi Fukuoka, Seiji Okada, Tetsuya Handa, Hitoshi Kurumizaka, Noriko Saitoh, Hiroshi Kimura, Yasuyuki Ohkawa   +11 more
doaj   +1 more source

Methylocystis sp. Strain SC2 Acclimatizes to Increasing NH4+ Levels by a Precise Rebalancing of Enzymes and Osmolyte Composition

mSystems, 2022
A high NH4+ load is known to inhibit bacterial methane oxidation. This is due to a competition between CH4 and NH3 for the active site of particulate methane monooxygenase (pMMO), which converts CH4 to CH3OH.
Kangli Guo, Anna Hakobyan, Timo Glatter, Nicole Paczia, Werner Liesack   +4 more
doaj   +1 more source