Primary central nervous system lymphoma and glioblastoma: differentiation using dynamic susceptibility-contrast perfusion-weighted imaging, diffusion-weighted imaging, and 18F-fluorodeoxyglucose positron emission tomography [PDF]
Satoshi Nakajima+9 more
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ABSTRACT Background Plasma p‐tau181 has proven to be a promising diagnostic and prognostic tool in the earliest phases of Alzheimer's disease (AD). We aimed to evaluate the prognostic role of p‐tau181 in predicting conversion to AD dementia and worsening in cognition in mild cognitive impairment (MCI) and subjective cognitive decline (SCD).
Giulia Giacomucci+12 more
wiley +1 more source
Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla+13 more
wiley +1 more source
Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation [PDF]
Ross Ferguson+2 more
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A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam+2 more
wiley +1 more source
Workflow of the parameter optimization process for ITSC fault detection, applying Differential Evolution optimization and the Smooth Pseudo Wigner‐Ville Distribution for signal processing. The optimized parameters are then used in the failure identification pipeline, which combines the signal processing with a YOLO‐based architecture for fault severity
Rafael Martini Silva+4 more
wiley +1 more source
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe+4 more
wiley +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source
Impulses in Differential Equations and Dynamical Systems
Many systems present a dynamic behavior that is characterized by the fact that at certain times they undergo a sudden change throughout their evolution. This situation is going to be studied in this memory. On the one hand, different techniques will be used to study some boundary value problems for impulsive differential equations.
openaire +1 more source
Magma Differentiation in Dynamic Mush Domains From the Perspective of Multivariate Statistics: Open‐ Versus Closed‐System Evolution [PDF]
Alessio Pontesilli+10 more
openalex +1 more source