Results 31 to 40 of about 2,287 (271)
Identifying nonlinear dynamical systems characterized by nonlinear parameters presents significant challenges in deriving mathematical models that enhance understanding of physical phenomena.
Siva Viknesh +3 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Locally conformal symplectic manifolds
A locally conformal symplectic (l. c. s.) manifold is a pair (M2n,Ω) where M2n(n>1) is a connected differentiable manifold, and Ω a nondegenerate 2-form on M such that M=⋃αUα (Uα- open subsets). Ω/Uα=eσαΩα, σα:Uα→ℝ, dΩα=0.
Izu Vaisman
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We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Fixed-Time Stability, Uniform Strong Dissipativity, and Stability of Nonlinear Feedback Systems
In this paper, we develop new necessary and sufficient Lyapunov conditions for fixed-time stability that refine the classical fixed-time stability results presented in the literature by providing an optimized estimate of the settling time bound that is ...
Wassim M. Haddad +2 more
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Chaos, comprehended characteristically, is the mathematical property of a dynamical system which is a deterministic mathematical model in which time can be either continuous or discrete as a variable.
Dumitru Baleanu, Yeliz Karaca
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The present paper describes, in a theoretical fashion, a variational approach to formulate fourth-order dynamical systems on differentiable manifolds on the basis of the Hamilton–d’Alembert principle of analytic mechanics.
Simone Fiori
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On automorphism groups of Toeplitz subshifts
On automorphism groups of Toeplitz subshifts, Discrete Analysis 2017:11, 19 pp. A discrete dynamical system is a space $X$ with some kind of structure, together with a map $\sigma\colon X\to X$ that preserves the structure.
Sebastian Donoso +3 more
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