Results 31 to 40 of about 9,147,708 (269)

On Max-Semistable Laws and Extremes for Dynamical Systems [PDF]

, 2021
Suppose (f,X,μ) is a measure preserving dynamical system and ϕ:X→R a measurable observable. Let Xi=ϕ∘fi−1 denote the time series of observations on the system, and consider the maxima process Mn:=max{X1,…,Xn}.
Holland, Mark P., Sterk, Alef E., Sterk, Alef E.; id_orcid, Mark P. Holland, Alef E. Sterk   +4 more
core   +2 more sources

Differential Dynamic Logic for Hybrid Systems

Journal of Automated Reasoning, 2008
AbstractHybrid systems are models for complex physical systems and are defined as dynamical systems with interacting discrete transitions and continuous evolutions along differential equations. With the goal of developing a theoretical and practical foundation for deductive verification of hybrid systems, we introduce a dynamic logic for hybrid ...
openaire   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Parametric Inequalities for s-Convex Stochastic Processes via Caputo Fractional Derivatives

Axioms
This paper establishes a general parametric integral identity involving (n+1)-times differentiable stochastic processes, formulated entirely in terms of stochastic k-Caputo fractional derivatives.
Ymnah Alruwaily, Rabab Alzahrani, Fatimah Alshahrani, Badreddine Meftah, Raouf Fakhfakh   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Substantiation of the backpropagation technique via the Hamilton—Pontryagin formalism for training nonconvex nonsmooth neural networks

Доповiдi Нацiональної академiї наук України
The paper observes the similarity between the stochastic optimal control over discrete dynamical systems and the lear ning multilayer neural networks. It focuses on contemporary deep networks with nonconvex nonsmooth loss and activation functions.
V.I. Norkin
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

ADAM-SINDy: An efficient optimization framework for parameterized nonlinear dynamical system identification

Physical Review Research
Identifying nonlinear dynamical systems characterized by nonlinear parameters presents significant challenges in deriving mathematical models that enhance understanding of physical phenomena.
Siva Viknesh, Younes Tatari, Chase Christenson, Amirhossein Arzani   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source