Results 31 to 40 of about 2,287 (271)

ADAM-SINDy: An efficient optimization framework for parameterized nonlinear dynamical system identification

open access: yesPhysical Review Research
Identifying nonlinear dynamical systems characterized by nonlinear parameters presents significant challenges in deriving mathematical models that enhance understanding of physical phenomena.
Siva Viknesh   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Locally conformal symplectic manifolds

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1985
A locally conformal symplectic (l. c. s.) manifold is a pair (M2n,Ω) where M2n(n>1) is a connected differentiable manifold, and Ω a nondegenerate 2-form on M such that M=⋃αUα (Uα- open subsets). Ω/Uα=eσαΩα, σα:Uα→ℝ, dΩα=0.
Izu Vaisman
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Fixed-Time Stability, Uniform Strong Dissipativity, and Stability of Nonlinear Feedback Systems

open access: yesMathematics
In this paper, we develop new necessary and sufficient Lyapunov conditions for fixed-time stability that refine the classical fixed-time stability results presented in the literature by providing an optimized estimate of the settling time bound that is ...
Wassim M. Haddad   +2 more
doaj   +1 more source

Advanced Fractional Mathematics, Fractional Calculus, Algorithms and Artificial Intelligence with Applications in Complex Chaotic Systems

open access: yesChaos Theory and Applications, 2023
Chaos, comprehended characteristically, is the mathematical property of a dynamical system which is a deterministic mathematical model in which time can be either continuous or discrete as a variable.
Dumitru Baleanu, Yeliz Karaca
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Coordinate-Free Variational Approach to Fourth-Order Dynamical Systems on Manifolds: A System and Control Theoretic Viewpoint

open access: yesMathematics
The present paper describes, in a theoretical fashion, a variational approach to formulate fourth-order dynamical systems on differentiable manifolds on the basis of the Hamilton–d’Alembert principle of analytic mechanics.
Simone Fiori
doaj   +1 more source

On automorphism groups of Toeplitz subshifts

open access: yesDiscrete Analysis, 2017
On automorphism groups of Toeplitz subshifts, Discrete Analysis 2017:11, 19 pp. A discrete dynamical system is a space $X$ with some kind of structure, together with a map $\sigma\colon X\to X$ that preserves the structure.
Sebastian Donoso   +3 more
doaj   +1 more source

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