Results 51 to 60 of about 2,287 (271)
Existence of Crossing Periodic Solutions of a Duffing Equation with Discontinuity
MathematicsClassical periodic solution theories of undamped Duffing equations are mostly restricted to continuous nonlinearities, while discontinuous models from mechanical impact and switching circuits lack systematic existence criteria for crossing periodic ...
Luming Li, Fangfang Jiang
doaj +1 more source
Differential Dynamic Programming for time-delayed systems [PDF]
2016 IEEE 55th Conference on Decision and Control (CDC), 2016 Trajectory optimization considers the problem of deciding how to control a dynamical system to move along a trajectory which minimizes some cost function. Differential Dynamic Programming (DDP) is an optimal control method which utilizes a second-order approximation of the problem to find the control.
David D. Fan, Evangelos A. Theodorou
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Everywhere Zero Pointwise Lyapunov Exponents for Sensitive Cellular Automata
, 2020 International audienceLyapunov exponents are an important concept in differentiable dynamical systems and they measure stability or sensitivity in the system.
Hotanen, Toni, Toni Hotanen
core +1 more source
Targeted Calibration to Adjust Stability Biases in Complex Dynamical System Models
Physical Review XModels of complex dynamical systems like the Earth’s climate often involve large numbers of uncertain parameters. Comprehensive exploration of the parameter space is typically prohibitive due to excessive computational costs, and systematic gradient ...
Daniel Pals +4 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Differentiable dynamical systems: an introduction to structural stability and hyperbolicity
, 2016 This is a graduate text in differentiable dynamical systems. It focuses on structural stability and hyperbolicity, a topic that is central to the field.
Wen, Lan
core
Steady Euler flows on $\mathbb{R}^3$ with wild and universal dynamics
, 2022 Understanding complexity in fluid mechanics is a major problem that has attracted the attention of physicists and mathematicians during the last decades.
Florio, Anna +8 more
core +1 more source