Results 71 to 80 of about 2,287 (271)
Zonal flow and spectra in two-dimensional Rayleigh–Bénard convection
In this thesis, we study two-dimensional Rayleigh-Bénard convection at a wide range of Prandtl numbers. Following two introductory chapters, the subsequent three chapters focus on a horizontally periodic domain with free-slip top and bottom boundaries ...
Winchester, Philip
core +2 more sources
The Weierstrass–Durand–Kerner root finder is not generally convergent
International audienceFinding roots of univariate polynomials is one of the fundamental tasks of numerics, and there is still a wide gap between root finders that are well understood in theory and those that perform well in practice.
Reinke, Bernhard +2 more
core +1 more source
Astrocyte heterogeneity in brain metastases
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
The mathematical research of William Parry FRS [PDF]
In this article we survey the mathematical research of the late William (Bill) Parry ...
Walters, Peter +3 more
core +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Emergence of wandering stable components
We prove the existence of a locally dense set of real polynomial automorphisms of C 2 displaying a wandering Fatou component; in particular this solves the problem of their existence, reported by Bedford and Smillie in 1991.
Berger, Pierre, Biebler, Sebastien
core
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source

