Results 81 to 90 of about 2,287 (271)

All, most, some differentiable dynamical systems

open access: yes, 2006
In the first part of this paper we study dynamical systems from the point of view of algebraic topology. What features of all dynamical systems are reflected by their actions on the homology of the phase space? In the second part we study recent progress
Shub, Michael
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Entropy and ergodic probability for differentiable dynamical systems and their bundle extensions

open access: yes, 2007
We answer a problem of Liao [S.T. Liao, Standard systems of differential equations and obstruction sets—from linearity to perturbations, in: System Researches, Proceedings Dedicated to the 85th Anniversary of Qian Xue-Sen, Zhejiang Education Press ...
Sun, Wenxiang, Vargas, Edson
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Bifurcacions genériques d'atractors en sistemes de reacció i difusió

open access: yes, 2021
In this work we write down in some detail the bifurcation theory of stationary states of reaction-diffusion equations. First, we prove, adapting notes of looss on the Navier-Stokes equations, that under some weak hypothesis a reaction-diffusion equation ...
Calsina i Ballesta, Àngel
core  

Dynamics of Generic Multidimensional Linear Differential Systems

open access: yesAdvanced Nonlinear Studies, 2008
Abstract We prove that there exists a residual subset R (with respect to the C 0 topology) of d-dimensional linear differential systems based in a μ-invariant flow and with transition matrix evolving in GL(d,ℝ) such that if A ∈ R, then, for μ-a.e.
openaire   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Integrating Deep Learning with the Theory of Nonlinear, Chaotic, and History-Dependent Dynamics

open access: yes, 2021
Deep learning approaches for modeling challenging dynamics are becoming more and more ubiquitous. However, as deep neural networks (DNNs) are not fully understood even in their own domain, interpretability of these models in dynamical settings can be a ...
Psenka, Michael
core  

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