Results 81 to 90 of about 2,681,020 (311)

Global dynamics of planar quasi-homogeneous differential systems [PDF]

arXiv, 2017
In this paper we provide a new method to study global dynamics of planar quasi--homogeneous differential systems. We first prove that all planar quasi--homogeneous polynomial differential systems can be translated into homogeneous differential systems and show that all quintic quasi--homogeneous but non--homogeneous systems can be reduced to four ...
arxiv  

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Dynamical systems model of development of the action differentiation in early infancy: a requisite of physical agency [PDF]

, 2022
Ryo Fujihira, Gentaro Taga
openalex   +2 more sources

Equivalence of planar dynamical and differential systems

Journal of Differential Equations, 1965
where x is a 2-vector, f(x) is homogeneous of degree N 3 1, g(x) is o (11 x 11”) for sufficiently small I] x I), and the usual existence and uniqueness properties hold for the solutions of each system close enough to the origin. The origin is assumed to be an isolated critical point of each system.A familiar problem is that of determining the local ...
openaire   +2 more sources

Time-preserving structural stability of hyperbolic differential dynamics with noncompact phase spaces [PDF]

arXiv, 2008
In this paper, we study the structural stability of hyperbolic differential systems on Euclidean spaces using Liao theory.
arxiv  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Stereographically conjugate differential systems [PDF]

arXiv, 2015
Topological bases of behaviour of trajectories for autonomous differential systems of the second order on sphere are stated. Stereographic atlas of trajectories is constructed. Differential connections between trajectories of stereographically conjugate differential systems are established.
arxiv  

Memory loss for nonequilibrium open dynamical systems

, 2014
We introduce a notion of conditional memory loss for nonequilibrium open dynamical systems. We prove that this type of memory loss occurs at an exponential rate for nonequilibrium open systems generated by one-dimensional piecewise-differentiable ...
Anushaya Mohapatra, W. Ott
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source