Results 41 to 50 of about 640,277 (338)
Differentiation and function of osteoclasts
The Keio Journal of Medicine, 2003 Osteoclasts, which are responsible for bone resorption, are rare cells with only 2-3 cells seen per 1 mm3 of bone. However, the loss of function in osteoclasts, problems with their differentiation and decrease in their number lead to bone osteosclerosis/osteopetrosis. On the other hand, an increase in their number or function induces bone osteoporosis,
Toshio Suda, Takeshi Miyamoto
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FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
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Differentiation of Interval Functions [PDF]
Proceedings of the American Mathematical Society, 1972 This paper is concerned with differentiation of interval functions appearing in interval analysis. Two definitions of a derivative are given; the first one uses an isometric restricted imbedding of the quasilinear space of intervals on the real line R, and the other definition is independent ofthat imbedding.
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FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Differentiability Properties of the Pre-Image Pressure
Discrete Dynamics in Nature and Society, 2012 We study the differentiability properties of the pre-image pressure. For a TDS (X,T) with finite topological pre-image entropy, we prove the pre-image pressure function Ppre(T,•) is Gateaux differentiable at f∈C(X,R) if and only if Ppre(T,•) has a unique
Kesong Yan, Fanping Zeng, Gengrong Zhang
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Advances in Difference Equations, 2020 In the article, we introduce the generalized exponentially μ-preinvex function, derive a new q-integral identity for second order q-differentiable function, and establish several new q-trapezoidal type integral inequalities for the function whose ...
Muhammad Uzair Awan +5 more
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Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Mean value problems of Flett type for a Volterra operator
Electronic Journal of Differential Equations, 2013 In this note we give a generalization of a mean value problem which can be viewed as a problem related to Volterra operators. This problem can be seen as a generalization of a result concerning the zeroes of a Volterra operator in the Banach space of ...
Cezar Lupu
doaj
Convexity-Preserving Rational Cubic Zipper Fractal Interpolation Curves and Surfaces
Mathematical and Computational Applications, 2023 A class of zipper fractal functions is more versatile than corresponding classes of traditional and fractal interpolants due to a binary vector called a signature.
Vijay, Arya Kumar Bedabrata Chand
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