Results 51 to 60 of about 274,031 (283)

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

Rank one and mixing differentiable flows

open access: yes, 2004
We construct, over some minimal translations of the two torus, special flows under a differentiable ceiling function that combine the properties of mixing and rank ...
Adams   +17 more
core   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Gateaux Differentiability of Convex Functions and Weak Dentable Set in Nonseparable Banach Spaces

open access: yesJournal of Function Spaces, 2019
In this paper, we prove that if C⁎⁎ is a ε-separable bounded subset of X⁎⁎, then every convex function g≤σC is Ga^teaux differentiable at a dense Gδ subset G of X⁎ if and only if every subset of ∂σC(0)∩X is weakly dentable.
Shaoqiang Shang, Yunan Cui
doaj   +1 more source

A new q-integral identity and estimation of its bounds involving generalized exponentially μ-preinvex functions

open access: yesAdvances in Difference Equations, 2020
In the article, we introduce the generalized exponentially μ-preinvex function, derive a new q-integral identity for second order q-differentiable function, and establish several new q-trapezoidal type integral inequalities for the function whose ...
Muhammad Uzair Awan   +5 more
doaj   +1 more source

Optimizing Non-Differentiable Metrics for Hashing

open access: yesIEEE Access, 2021
Image hashing embeds the image to binary codes which can boost the efficiency of approximately nearest neighbors search. F-measure is a widely-used metric for evaluating the performance of hashing methods.
Yiwen Wei, Dayong Tian, Jiao Shi, Yu Lei
doaj   +1 more source

Differentiating matrix functions [PDF]

open access: yesOperators and Matrices, 2013
Multivariable, real-valued functions induce matrix-valued functions defined on the space of d-tuples of n-times-n pairwise-commuting self-adjoint matrices. We examine the geometry of this space of matrices and conclude that the best notion of differentiation of these matrix-valued functions is differentiation along curves.
openaire   +2 more sources

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa   +8 more
wiley   +1 more source

Punzi-loss:

open access: yesEuropean Physical Journal C: Particles and Fields, 2022
We present the novel implementation of a non-differentiable metric approximation and a corresponding loss-scheduling aimed at the search for new particles of unknown mass in high energy physics experiments.
F. Abudinén   +45 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

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