Results 41 to 50 of about 2,011 (255)

On a class of differential-algebraic equations with infinite delay

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2011
We study the set of $T$-periodic solutions of a class of $T$-periodically perturbed Differential-Algebraic Equations, allowing the perturbation to contain a distributed and possibly infinite delay.
Luca Bisconti, Marco Spadini
doaj   +1 more source

Local low-rank approach to nonlinear matrix completion

open access: yesEURASIP Journal on Advances in Signal Processing, 2021
This paper deals with a problem of matrix completion in which each column vector of the matrix belongs to a low-dimensional differentiable manifold (LDDM), with the target matrix being high or full rank.
Ryohei Sasaki   +3 more
doaj   +1 more source

Assessment of Complex System Dynamics via Harmonic Mapping in a Multifractal Paradigm

open access: yesMathematics, 2021
In the present paper, nonlinear behaviors of complex system dynamics from a multifractal perspective of motion are analyzed. In the framework of scale relativity theory, by analyzing the dynamics of complex system entities based on continuous but non ...
Gabriel Gavriluț   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Reduction of Bundles, Connection, Curvature, and Torsion of the Centered Planes Space at Normalization

open access: yesMathematics, 2019
The space Π of centered m-planes is considered in projective space P n . A principal bundle is associated with the space Π and a group connection is given on the principal bundle. The connection is not uniquely induced at the
Olga Belova
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Differentiability in Fréchet spaces and delay differential equations

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2019
In infinite-dimensional spaces there are non-equivalent notions of continuous differentiability which can be used to derive the familiar results of calculus up to the Implicit Function Theorem and beyond.
Hans-Otto Walther
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy