Results 101 to 110 of about 6,108,581 (281)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

A class of linear differential-difference equations [PDF]

Pacific Journal of Mathematics, 1960
Slater, Morton, Wilf, Herbert S.
openaire   +2 more sources

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Finite Difference Method for Two-Dimensional Fractional Partial Differential Equation with parameter

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
 In this paper, we introduce and discuss an algorithm for the numerical solution of two- dimensional fractional partial differential equation with parameter.
I. I. Gorial
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Software DSamala Toolbox para el análisis y la simulación de sistemas dinámicos discretos, continuos y estocásticos

Ingeniería e Investigación, 2012
En este artículo se describe una herramienta computacional para la simulación y el análisis de sistemas dinámicos discretos, continuos y estocásticos. Esta herramienta, denominada DSamala Toolbox, se presenta como un Toolbox de Matlab.
Angelica María Atehortúa Labrador, Lilia Mercedes Ladino Martínez, Jose Carlos Valverde Fajardo   +2 more
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Exact Solutions for Nonlinear Differential Difference Equations in Mathematical Physics

Abstract and Applied Analysis, 2013
We modified the truncated expansion method to construct the exact solutions for some nonlinear differential difference equations in mathematical physics via the general lattice equation, the discrete nonlinear Schrodinger with a saturable nonlinearity ...
Khaled A. Gepreel, Taher A. Nofal, Fawziah M. Alotaibi   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Riccati technique and nonoscillation of damped linear dynamic equations with the conformable derivative on time scales

Results in Applied Mathematics
In this study, we investigate the use of damped linear dynamic equations with the conformable derivative on time scales to provide sufficient conditions to guarantee nonoscillation for nontrivial solutions of both ordinary differential and discrete ...
Kazuki Ishibashi
doaj   +1 more source