Results 81 to 90 of about 6,108,581 (281)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

The compact eighth-order of approximation difference schemes for fourth-order differential equation

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
Local and nonlocal boundary value problems (LNBVPs) related to fourth-order differential equations (FODEs) were explored. To tackle these problems numerically, we introduce novel compact four-step difference schemes (DSs) that achieve eighth-order of ...
A. Ashyralyev, I.M. Ibrahim
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

NEW EXAMPLE OF FINITE-DIMENSIONAL REDUCTION OF A DISCRETE CHAIN OF THE TODA CHAIN TYPE

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2020
Background. Integrable discrete equations considered in the framework of the numerical study of their continuous analogs. Same time continuous equations obtained using the limit from the discrete systems.
T. G. Kazakova, R. R. Sattarova
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Extrapolation methods for first order ordinary differential equations [PDF]

open access: yes, 1980
Given a system of fist order differential equations, whose coefficient matrix has constant elements, with initial conditions specified, a family of extrapolating algorithms based on Pade approximants to the exponential function is developped.
Twizell, E H
core   +3 more sources

Jacobi Elliptic Solutions for Nonlinear Differential Difference Equations in Mathematical Physics

open access: yesJournal of Applied Mathematics, 2012
We put a direct new method to construct the rational Jacobi elliptic solutions for nonlinear differential difference equations which may be called the rational Jacobi elliptic functions method.
Khaled A. Gepreel, A. R. Shehata
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy