Results 41 to 50 of about 24,433 (239)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Numerical methods for ordinary differential equations with applications to partial differential equations [PDF]

, 1983
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The thesis develops a number of algorithms for the numerical solution of ordinary differential equations with applications to partial differential equations.
Khaliq, Abdul Qayyum Masud
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Comparing one-shot and multi-shot methods for solving periodic of Riccati differential equations [PDF]

, 2007
- One-shot methods and recently proposed multi-shot methods for computing stabilizing solutions of continuoustime periodic Riccati differential equations are examined and evaluated on two test problems.
Varga, Andreas, Johansson, S., Shiriaev, A.   +2 more
core  

Composite Function Antiderivative Transformation Iterative Deep Learning Solution Method for Hyper-fine Group Resonance Self-shielding Calculation in Homogeneous System

Yuanzineng kexue jishu
Resonance self-shielding calculations are crucial in reactor physics analysis and core design computation, as they serve as a preliminary step for conducting neutron transport or diffusion calculations based on macroscopic cross sections.
LIU Dong1, 2, CHEN Qilong1, 2, ZHANG Qian3, YU Jialei4
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Numerical modelling of some systems in the biomedical sciences [PDF]

, 1998
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Finite-difference numerical methods are developed for the solution of some systems in the biomedical sciences; namely, a predator-prey model and the SEIR ...
Al-Showaikh, F.N.M., Al-Showaikh, Faisal
core  

Design and Technological Aspects of Integrating Multi-Blade Machining and Surface Hardening on a Single Machine Base

Journal of Manufacturing and Materials Processing
Modern mechanical engineering faces high competition in global markets, which requires manufacturers of process equipment to significantly reduce production costs while ensuring high product quality and maximum productivity.
Vadim Skeeba, Vladimir Ivancivsky, Aleksey Chernikov, Nikita Martyushev, Nikita Vakhrushev, Kristina Titova   +5 more
doaj   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source