Results 31 to 40 of about 2,372,273 (212)
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
A Differential Response Functioning Framework for Understanding Item, Bundle, and Test Bias [PDF]
This dissertation extends the parametric sampling method and area-based statistics for differential test functioning (DTF) proposed by Chalmers, Counsell, and Flora (2016).
Chalmers, Robert Philip Sidney
core
Full-field optical coherence tomography using a fibre imaging bundle [PDF]
An imaging fibre bundle is demonstrated for spatially-multiplexed probe beam delivery in OCT, with the aim of eliminating the mechanical scanning currently required at the probe tip in endoscopic systems.
H. D. Ford +3 more
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Measurement invariance and Differential Item Functioning (DIF) [PDF]
Lecture slides for Measurement invariance and Differential Item Functioning ...
Croudace, Tim, Brown, Anna
core +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Investigating the Effects of Differential Item Functioning on Proficiency Classification
This study provides a comprehensive evaluation of the effects of differential item functioning (DIF) on proficiency classification. Using Monte Carlo simulation, item- and test-level DIF magnitudes were varied systematically to investigate their impact ...
Bo Zhang, Logan Rome
core +1 more source

