Results 171 to 180 of about 2,730,068 (332)

Comparative analysis of the effects of different purification methods on the yield and purity of cow milk extracellular vesicles

Journal of Extracellular Biology
Isolation of extracellular vesicles (EV) has been developing rapidly in parallel with the interest in EVs. However, commonly utilized protocols may not suit more challenging sample matrixes and could potentially yield suboptimal results.
Santeri Kankaanpää, Markus Nurmi, Markus Lampimäki, Heidi Leskinen, Anni Nieminen, Anatoliy Samoylenko, Seppo J. Vainio, Sari Mäkinen, Lauri Ahonen, Juha Kangasluoma, Tuukka Petäjä, Sirja Viitala   +11 more
doaj   +1 more source

Differential Effects of Inhibitors on Respiratory Activity of Synchronous Cultures of Bacillus subtilis Prepared by Continuous-flow Centrifugation

, 1981
C. Edwards, R. J. McCann
openalex   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

FEATURES OF CALCULATION OF CENTRIFUGED AND VIBRO-CENTRIFUGED REINFORCED CONCRETE STRUCTURES BY DIFFERENTIAL CONSTRUCTION CHARACTERISTICS OF CONCRETE

, 2021
Levon R. Mailyan, Sergey A. Stel’makh, Evgenii M. Shcherban’, Natal’ya Dotsenko   +3 more
openalex   +2 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Quantification of surfactant pool sizes in rabbit lung during perinatal development.

Journal of Lipid Research, 1988
Methods are presented for the quantitative isolation of surfactants from fetal and newborn rabbit alveolar lavage returns and post-lavaged lung tissue homogenates.
M Oulton, M Fraser, M Dolphin, R Yoon, G Faulkner   +4 more
doaj  

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Differential centrifugation and microfiltration for the identification of nanovesicle associated miRNome in human serum.

, 2013
de Candia Paola, A Torri, Gorletta Tatiana, Maya Fedeli, Elisabetta Bulgheroni, Cheroni Cristina, Marabita Francesco, Crosti Mariacristina, Moro Monica, Pariani Elena, Romanò Luisa, Esposito Susanna, Fabio Mosca, Rossetti Grazisa, L. Rossi Riccardo, Geginat Jens, Casorati Giulia, Paolo Dellabona, Massimiliano Pagani, Abrignani Sergio   +19 more
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source