Results 191 to 200 of about 273,854 (260)

Plant-Derived Exosome-Like Nanoparticles: A Promising Therapeutic for Neurological Disorders and Drug Delivery. [PDF]

Int J Nanomedicine
Zheng M, Hong X, Liao P, Huang H, Zhang Y, Xu W, Li H.   +6 more
europepmc   +1 more source

Hepatic Mitochondrial Isolation Protocol in the Seahorse Hippocampus erectus Using Differential Centrifugation v1 [PDF]

Ana Karen Meza-Buendia, Ignacio Navarrete, Kiara Nicole Gajardo López, Maite Mascaro Miquelajauregui, Carlos Rosas   +4 more
openalex   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Comparative Assessment of Whole Organ Tissue Processing Methods for the Isolation of Extracellular Vesicles From Intact Organs. [PDF]

J Extracell Vesicles
Hussain MT, Austin-Williams S, McCay J, Hayat H, Wright TD, Christoforou M, Ykema E, Perretti M, Cooper D, Margraf A.   +9 more
europepmc   +1 more source

Differential centrifugation and microfiltration for the identification of nanovesicle associated miRNome in human serum.

, 2015
de Candia Paola, A Torri, Gorletta Tatiana, Maya Fedeli, Elisabetta Bulgheroni, Cheroni Cristina, Marabita Francesco, Crosti Mariacristina, Moro Monica, Pariani Elena, Romanò Luisa, Esposito Susanna, Fabio Mosca, Rossetti Grazisa, L. Rossi Riccardo, Geginat Jens, Casorati Giulia, Paolo Dellabona, Massimiliano Pagani, Abrignani Sergio   +19 more
openalex   +2 more sources

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Protocol for endolysosomal proteomics in goat atrial tissue using a refined density-gradient approach. [PDF]

STAR Protoc
Ayagama T, Berridge G, Fischer R, Capel RA, Verheule S, Schotten U, Burton RAB.   +6 more
europepmc   +1 more source

Advanced liquid centrifuge using differentially rotating cylinders and optimized boundary conditions, and methods for the separation of fluids

, 2023
Hantao Ji
openalex   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source