Results 111 to 120 of about 6,922,407 (400)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Diagnóstico diferencial do transtorno obsessivo-compulsivo

open access: yesBrazilian Journal of Psychiatry, 2001
Obsessive-compulsive disorder (OCD) has clinical features that overlap in various degrees with many other mental disorders. As a result, the differential diagnosis sometimes can be difficult. This review briefly summarizes the phenomenologic similarities
Albina R Torres
doaj   +1 more source

Differential Diagnosis of Glaucoma

open access: yes, 2019
Glaucoma is the most commonly acquired visual neuropathy and the main cause of irreversible loss of vision.It is characterized by degeneration of retinal ganglion cells resulting in morphology changes of the optic nerve head (ONH). It may be asymptomatic even at an advanced stage, so the diagnosis is often delayed.
Tzamouranis, Dorotheos Dimitrios   +1 more
openaire   +1 more source

Case report : Williams-Campbell syndrome [PDF]

open access: yes, 2009
Background: Williams-Campbell syndrome is a rare type of bronchiectasis that is due to deficiency or absence of cartilage in the fourth- to sixth-order bronchi.
Bestry, Iwona   +3 more
core  

Neural network-based colonoscopic diagnosis using on-line learning and differential evolution [PDF]

open access: yes, 2004
In this paper, on-line training of neural networks is investigated in the context of computer-assisted colonoscopic diagnosis. A memory-based adaptation of the learning rate for the on-line back-propagation (BP) is proposed and used to seed an on-line ...
Battiti   +18 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Panniculitides in an internist's practice

open access: yesТерапевтический архив, 2014
By panniculitides is meant a group of heterogeneous inflammatory diseases characterized by the involvement of subcutaneous adipose tissue. A diversity of their forms and variants of their course determines the need for careful patent examination to ...
B S Belov   +3 more
doaj  

The Admissibility of Differential Diagnosis Testimony to Prove Causation in Toxic Tort Cases: The Interplay of Adjective and Substantive Law [PDF]

open access: yes, 2001
This article uses the differential diagnosis opinions to explore a pair of interrelationships. The basic causal framework employed by most courts in toxic tort cases is presented.
Machal-Fulks, Julie, Sanders, Joseph
core   +1 more source

A 45-year-old Female with an Atypical Presentation of Pharyngitis [PDF]

open access: yes, 2020
Introduction: Emergency physicians are trained to treat a variety of ailments in the emergency department (ED), some of which are emergent, while others are not. A common complaint seen in the ED is a sore throat.
Carney, Michael B.   +4 more
core  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

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