Results 111 to 120 of about 4,241,694 (259)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Mediastinal lymphomas: Differential diagnosis [PDF]
Vojnosanitetski Pregled, 2008 Mihaljević Biljana +7 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Status epilepticus in the elderly: differential diagnosis and treatment
Neuropsychiatric Disease and Treatment, 2011 Elizabeth Ann Mauricio, William David FreemanMayo Clinic, Jacksonville, FL, USADate of Preparation 28th January 2011 Conflict of interest: None declaredAbstract: Seizures are not an uncommon occurrence in older adults, and the incidence of status ...
Mauricio EA, Freeman WD
doaj
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
, 2018 Mei Mei,1 Ligang Ye,2 Juan Quan,1 Pintong Huang1 1Department of Ultrasound, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China; 2Department of Emergency, The Second Affiliated Hospital, Zhejiang University ...
Mei M, Huang PT, Ye LG, Quan J
core
Restless legs syndrome: differential diagnosis and management with rotigotine
Neuropsychiatric Disease and Treatment, 2009 Giovanni Merlino1,3, Anna Serafini1, Francesca Robiony2, Mariarosaria Valente1,3, Gian Luigi Gigli1,31Sleep Disorder Center, Neurology and Clinical Neurophysiology; 2Pharmacy Unit, Santa Maria della Misericordia University Hospital, Udine, Italy; 3DPMSC,
Giovanni Merlino +4 more
doaj
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Dermoscopy of Primary Localized Cutaneous Nodular Amyloidosis
Clinical, Cosmetic and Investigational DermatologyLaura Manuela Pulgarin,1 Alessandro De Pellegrin,2 Giuseppe Stinco,3 Enzo Errichetti3 1Department of Dermatology, Universidad del Valle, Cali, Colombia; 2Department of Pathology, Udine “S.
Pulgarin LM +3 more
doaj
Metachondromatosis: Clinical and radiological diagnosis and differential diagnosis
Case Reports, 2016 The clinical case of a 9-year-old patient derived from Orthopedics to the Institute of Genetics at Universidad Nacional de Colombia due to a longstanding medical history of multiple bony outgrowths that required surgical management without etiologic ...
Karym Zahir Halaby -Hernández +4 more
doaj