Results 121 to 130 of about 7,125,193 (404)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

The syndrome of catatonia [PDF]

Halo 194, 2020
The syndrome of catatonia presents as damage of willful activity often in association with mood disorders, catatonic schizophrenia, conversion disorders, neurological disease, metabolic disorders, toxic infections of the nervous system, viral infections ...
Milinović Milica, Todorović Marko
doaj  

Learning Optimal Deep Projection of $^{18}$F-FDG PET Imaging for Early Differential Diagnosis of Parkinsonian Syndromes

, 2018
Several diseases of parkinsonian syndromes present similar symptoms at early stage and no objective widely used diagnostic methods have been approved until now.
AJ Hughes, CC Tang, D Eidelberg, D Zhang, F Gao, G Litjens, HI Suk, J Jiao, L Bi, L Zhou, R Li, S Fahn, S Lu, U Bagci, VK Ithapu, Y LeCun, Z Xu   +16 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Diagnóstico diferencial do transtorno obsessivo-compulsivo

Brazilian Journal of Psychiatry, 2001
Obsessive-compulsive disorder (OCD) has clinical features that overlap in various degrees with many other mental disorders. As a result, the differential diagnosis sometimes can be difficult. This review briefly summarizes the phenomenologic similarities
Albina R Torres
doaj   +1 more source

Diagnosis, differential diagnosis and misdiagnosis of Susac syndrome [PDF]

, 2022
James Triplett, Jessica Qiu, Billy O’Brien, Sumana Gopinath, Benjamin Trewin, Penelope J. Spring, Mohamed Shaffi, Jerome Ip, Fiona Chan, Luke Chen, Ian Wilson, Claire Muller, Heidi Beadnall, Mike Boggild, Anneke van der Walt, Richard Roxburgh, Nabil Seery, Tomáš Kalinčík, Michael Barnett, John DE Parratt, Stephen Reddel, B. Tsang, Todd A. Hardy   +22 more
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Cryptogenic organizing pneumonia - wrongfully neglected disease [PDF]

Srpski Arhiv za Celokupno Lekarstvo
Introduction. Cryptogenic organizing pneumonia (COP) is a type of organizing pneumonia with an unknown primary etiology. Diagnosis of COP requires exclusion of any other possible cause.
Sekulović-Radovanović Ivana, Marković Filip, Stjepanović Mihailo, Čolić Nikola, Marić Dragana   +4 more
doaj   +1 more source

Childhood obesity complicating the differential diagnosis of maturity-onset diabetes of the young and type 2 diabetes [PDF]

, 2007
Naomi Weintrob, Eti Stern, Yaffa Klipper-Aurbach, Moshe Phillip, Galia Gat‐Yablonski   +4 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source