Results 191 to 200 of about 6,761,743 (311)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Differential distribution of fibrovascular proliferative membranes in 25-gauge vitrectomy for proliferative diabetic retinopathy. [PDF]

Int J Ophthalmol
Lu N, Yang SL, Guo S, Yang DN, Liu L, Fan CH, Guo Y, Liu J, Zhao W.   +8 more
europepmc   +1 more source

Differential Distribution of RBPMS in Pig, Rat, and Human Retina after Damage. [PDF]

Int J Mol Sci, 2020
Pereiro X, Ruzafa N, Urcola JH, Sharma SC, Vecino E.   +4 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Income Distribution In Brazil 1981-1990 Parametric and Non-Parametric Approach

, 1999
We examine changes in the shape of the Brazilian income distribution during the “lost decade” of the 1980s, using a recently available comprehensive micro-data set.
Ferreira, Francisco H.G., Litchfield, Julie A., Cowell, Frank A.   +2 more
core  

Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles. [PDF]

Neural Regen Res
Liu Y, Huang W, Wen J, Xiong X, Xu T, Wang Q, Chen X, Zhao X, Li S, Li X, Yang W.   +10 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Three-stages tectonic evolution controls the differential distribution of hydrocarbons in the West Java backarc basin. [PDF]

Sci Rep
Zhou Z, Peng W, Sun H, Fu X, Zhu W.
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Government Policy and Equality of Income Distribution in the Netherlands (1945-1986)

, 1992
Inequality of income distribution in the Netherlands has since 1945 strongly been influenced by government policies. Until the end of the 1970s, governments pursued policies designed to reduce income differentials.
van Wijngaarden, P.
core