Results 61 to 70 of about 6,761,743 (311)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Inequality and Growth : Why Differential Fertility Matters [PDF]
We argue the inequality and growth are linked through differential fertility and the accumulation of human capital. We build an overlapping-generations model in which dynasties differ in their initial endowment with human capital.
DE LA CROIX, David, DOEPKE, Matthias
core
Application of 5G to current differential protection of distribution network
Dianxin kexue, 2020 Driven by the strategy of grid as a Platform,Hub,and Sharing as well as the construction of Energy Internet and Ubiquitous power Internet of Things declared by Sate Grid Corporation of China,the intelligent distribution network evolves towards ...
Yuxiang LV +3 more
doaj +2 more sources
Differentially Private Sampling from Distributions
SIAM Journal on Computing44 pages, preliminary version in NeurIPS ...
Sofya Raskhodnikova +3 more
openaire +6 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Modelling Income Using the Generalised Lambda Distribution
, 2008 In the present article we propose the generalised lambda distribution as a model for income data. The quantile measures of location, dispersion, skewness, and kurtosis of the distribution are matched against the corresponding measures derived from the ...
Nair, K.R. Muraleedharan +2 more
core
Differential Phase Encoded Plug-and-Play Measurement-Device-Independent Quantum Key Distribution
IEEE Transactions on Quantum EngineeringMeasurement-device-independent quantum key distribution (MDI-QKD) enhances security by removing vulnerabilities associated with detector side channels. Real-world implementations ofMDI-QKD face practical challenges, such as channel asymmetry and physical
Nilesh Sharma +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source