Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Consumption, Income Distribution and Taxation: Keynes’ Fiscal Policy
The General Theory argued that income distribution affected consumption. Greater income inequality put more money into the hands of people with higher MPCs, leading to increased consumption; and inequality had the reverse impact.
Pressman, Steven
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
A Labor Market Theory of Earnings Distribution
A simple theory of the labor market is presented in which the short end of the market sells. A flexible parameterisation of the theory yields an earnings distribution density function which is closely approximated by the well-known beta and gamma ...
Parker, Simon Charles
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Brownian motion and exposed solutions of differential inclusions [PDF]
We present a research program designed by A. Bressan and some partial results related to it. First, we construct a probability measure supported on the space of solutions to a planar differential inclusion, where the right-hand side is a Lipschitz ...
Vladimir V. Goncharov +2 more
core +1 more source
Differential protection of distribution network based on 5G and particle swarm algorithm
Differential protection has excellent selectivity and quick motion, which is suitable for distribution network protection scenarios of multi-source networks.
HAO Hanbing +4 more
doaj +1 more source
Practical round-robin differential-phase-shift quantum key distribution
The security of quantum key distribution (QKD) relies on the Heisenberg uncertainty principle, with which legitimate users are able to estimate information leakage by monitoring the disturbance of the transmitted quantum signals.
Zhen Zhang +3 more
doaj +1 more source
Vertical differentiation beyond the uniform distribution
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Benassi, Corrado +2 more
openaire +3 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

