High-Precision Detection of Magnetic Nanoparticles in Microfluidic Biosensing Systems. [PDF]
Brown D +5 more
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
<i>In vitro</i> interspecies interactions between methicillin-resistant <i>Staphylococcus aureus</i> and <i>Pseudomonas aeruginosa</i>: effects on bacterial growth, antibiotic susceptibility, and transcriptomic reprogramming. [PDF]
Peng X +18 more
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
b -Hurwitz numbers from refined topological recursion. [PDF]
Kumar Chidambaram N +2 more
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Discovering physical laws with parallel symbolic enumeration. [PDF]
Ruan K +6 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
A digital plating platform for robust and versatile microbial detection and analysis. [PDF]
Hu T, Han X, Wu L, Sun B, Li G.
europepmc +1 more source
Disentangling temporal integration and segregation in multiple object individuation. [PDF]
Huang Y +7 more
europepmc +1 more source

