Results 111 to 120 of about 6,531,183 (350)

Lumé's Differential Equation [PDF]

Proceedings of the London Mathematical Society, 1888
n ...
openaire   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Solving system of integro differential equations using discrete adomian decomposition method

Journal of Taibah University for Science, 2019
In this paper, we propose a new numerical method for solving system of integro-differential equations featuring Volterra and Fredholm integrals. The proposed method depends on the successful application of the Discrete Adomian Decomposition Method (DADM)
H. O. Bakodah, M. Al-Mazmumy, S. O. Almuhalbedi   +2 more
doaj   +1 more source

Boundary value and expansion problems of ordinary linear differential equations [PDF]

, 1908
George D. Birkhoff
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Existence of Solution to Nonlinear Third-Order Differential Equation and Iterative Method Utilization via Graph-Based Contraction

Mathematics
A new kind of graph-based contraction in a metric space is introduced in this article. We investigate results concerning the best proximity points and fixed points for these contractions, supported by illustrated examples.
Kanyuta Poochinapan, Sompop Moonchai, Tanadon Chaobankoh, Phakdi Charoensawan   +3 more
doaj   +1 more source

The Solutions of Emden's and Similar Differential Equations [PDF]

, 1930
Russell Fowler
openalex   +1 more source

On combinatorial differential equations

Journal of Mathematical Analysis and Applications, 1986
This article analyzes the solution set of a first order initial value differential problem of the form \(dy/dx=f(x,y)\), \(y(0)=0\) in the context of combinatorial species in the sense of A. Joyal. It turns out that many non-isomorphic combinatorial solutions are possible for a given problem, although they all have the same underlying generating series.
openaire   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source