Results 41 to 50 of about 1,822,413 (315)

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Quantized Black Hole and Heun function

open access: yes, 2012
Following the simple proposal by He and Ma for quantization of a black hole(BH) by Bohr's idea about the atoms, we discussed the solvability of the wave equation for such a BH. We superficial solved the associated Schrodinger equation.
D. Momeni   +3 more
core   +1 more source

Riccati Differential Equation for Hypergeometric Differential Equation

open access: yesRendiconti del Seminario Matematico della Università di Padova, 2012
In this paper, we study the solutions of Riccati differential equation corresponding to p -adic differential equations which are solvable on the generic disc.
openaire   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

On the fractional Allee logistic equation in the Caputo sense

open access: yesExamples and Counterexamples, 2023
In the framework of population models, logistic growth and fractional logistic growth has been analyzed. In some situations the so-called Allee effect gives more accurate approximation.
I. Area, Juan J. Nieto
doaj   +1 more source

Teaching Partial Differential Equations with CAS [PDF]

open access: yes, 2018
Partial Differential Equations (PDE) are one of the topics where Engineering students find more difficulties when facing Math subjects. A basic course in Partial Differential Equations (PDE) in Engineering, usually deals at least, with the following ...
Aguilera-Venegas, Gabriel   +5 more
core  

Integral representation of solutions to Fuchsian system and Heun's equation

open access: yes, 2007
We obtain integral representations of solutions to special cases of the Fuchsian system of differential equations and Heun's differential equation. In particular, we calculate the monodromy of solutions to the Fuchsian equation that corresponds to Picard'
Belokolos   +19 more
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Ulam Stability of n-th Order Delay Integro-Differential Equations

open access: yesMathematics, 2021
In this paper, the Ulam stability of an n-th order delay integro-differential equation is given. Firstly, the existence and uniqueness theorem of a solution for the delay integro-differential equation is obtained using a Lipschitz condition and the ...
Shuyi Wang, Fanwei Meng
doaj   +1 more source

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