Results 61 to 70 of about 382,650 (266)
Most fundamental themes in mathematical physics and modern engineering are investigated by the closed form traveling wave solutions of nonlinear evolution equations.
M. Mamun Miah +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Initial value problems of fractional order Hadamard-type functional differential equations
The Banach fixed point theorem and a nonlinear alternative of Leray-Schauder type are used to investigate the existence and uniqueness of solutions for fractional order Hadamard-type functional and neutral functional differential equations.
Bashir Ahmad, Sotiris K. Ntouyas
doaj
In this article, we consider the existence of solutions to the Sturm–Liouville differential equation with random impulses and boundary value problems.
Zihan Li, Xiao-Bao Shu, Tengyuan Miao
doaj +1 more source
In this paper, we study the semi-Hyers–Ulam–Rassias stability and the generalized semi-Hyers–Ulam–Rassias stability of some partial differential equations using Laplace transform. One of them is the convection partial differential
Daniela Marian
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Periodic solution for a delay integro-differential equation in biomathematics
Sufficient conditions for the existence and uniqueness of periodic solution of a delay integro-differential equation which arise in biomathematics are given.
Bica, Alexandru Mihai, Muresan, Sorin
core
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source

