Results 71 to 80 of about 5,148,909 (356)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Cotton-Type and Joint Invariants for Linear Elliptic Systems

The Scientific World Journal, 2013
Cotton-type invariants for a subclass of a system of two linear elliptic equations, obtainable from a complex base linear elliptic equation, are derived both by spliting of the corresponding complex Cotton invariants of the base complex equation and from
A. Aslam, F. M. Mahomed
doaj   +1 more source

Variational Approach for the Reconstruction of Damaged Optical Satellite Images Through Their Co-Registration with Synthetic Aperture Radar

Journal of Optimization, Differential Equations and Their Applications, 2020
In this paper the problem of reconstruction of damaged multi-band optical images is studied in the case where we have no information about brightness of such images in the damage region. Mostly motivated by the crop field monitoring problem, we propose a
Peter I. Kogut, Mykola V. Uvarov
doaj   +1 more source

Stochastic Differential Equations

Journal of Multivariate Analysis, 1974
AbstractWhen a system is acted upon by exterior disturbances, its time-development can often be described by a system of ordinary differential equations, provided that the disturbances are smooth functions. But for sound reasons physicists and engineers usually want the theory to apply when the noises belong to a larger class, including for example ...
openaire   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

A Note on the Solutions of Some Nonlinear Equations Arising in Third-Grade Fluid Flows: An Exact Approach

The Scientific World Journal, 2014
In this communication, we utilize some basic symmetry reductions to transform the governing nonlinear partial differential equations arising in the study of third-grade fluid flows into ordinary differential equations.
Taha Aziz, F. M. Mahomed
doaj   +1 more source

SUCCESSIVE ITERATIVE METHOD FOR HIGHER-ORDER FRACTIONAL DIFFERENTIAL EQUATIONS INVOLVING STIELTJES INTEGRAL BOUNDARY CONDITIONS

TASK Quarterly, 2016
In this paper, the existence of positive solutions to fractional differential equations with delayed arguments and Stieltjes integral boundary conditions is discussed.
TADEUSZ JANKOWSKI
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Removability conditions for anisotropic parabolic equations in a computational validation

Frontiers in Applied Mathematics and Statistics
The article investigates removability conditions for singularities of anisotropic parabolic equations and in particular for the anisotropic porous medium equation and it aims in the numerical validation of the analytical results. The preconditions on the
Dirk Langemann, Mariia Savchenko, Mariia Savchenko   +2 more
doaj   +1 more source

Functional differential equations close to differential equations [PDF]

Bulletin of the American Mathematical Society, 1966
when the lag function r(t) is nearly constant for large /, and has also asked for conditions on the function r under which all solutions approach zero as t—» oo. The purpose of this announcement is to initiate a study of various stability and oscillation problems for equations with perturbed lag functions, and to suggest that a modification of the ...
openaire   +2 more sources