Results 71 to 80 of about 2,445,513 (291)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
TASK Quarterly, 2016 In this paper, we give some new results for multiplicity of positive (nonnegative) solutions for third-order differential equations with derivative dependence, deviating arguments and Stieltjes integral boundary conditions.
TADEUSZ JANKOWSKI
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
FRACTIONAL PROBLEMS WITH RIGHT-HANDED RIEMANN-LIOUVILLE FRACTIONAL DERIVATIVES
TASK Quarterly, 2016 In this paper, we investigate the existence of solutions for advanced fractional differential equations containing the right-handed Riemann-Liouville fractional derivative both with nonlinear boundary conditions and also with initial conditions given at
TADEUSZ JANKOWSKI
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Removability conditions for anisotropic parabolic equations in a computational validation
Frontiers in Applied Mathematics and StatisticsThe article investigates removability conditions for singularities of anisotropic parabolic equations and in particular for the anisotropic porous medium equation and it aims in the numerical validation of the analytical results. The preconditions on the
Dirk Langemann +2 more
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Cotton-Type and Joint Invariants for Linear Elliptic Systems
The Scientific World Journal, 2013 Cotton-type invariants for a subclass of a system of two linear elliptic equations, obtainable from a complex base linear elliptic equation, are derived both by spliting of the corresponding complex Cotton invariants of the base complex equation and from
A. Aslam, F. M. Mahomed
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TASK Quarterly, 2016 In this paper, the existence of positive solutions to fractional differential equations with delayed arguments and Stieltjes integral boundary conditions is discussed.
TADEUSZ JANKOWSKI
doaj +1 more source
Difference–Differential Equations [PDF]
Nature, 1948 THE general linear homogeneous difference–differential equation with constant coefficients is where 0 ⩽ μ ⩽m, 0⩽ν ⩽ n, y(ν)(t) is the ν-th derivative of the unknown function y (t) and 0 = b0 bm, if amn≠ 0. (2) Was first given by Hilb8, but under conditions which would exclude most of the applications.
openaire +1 more source