Results 51 to 60 of about 4,901 (302)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Feller semigroups, Lp-sub-Markovian semigroups, and applications to pseudo-differential operators with negative definite symbols [PDF]

, 2001
The question of extending L-p-sub-Markovian semigroups to the spaces L-q, q > P, and the interpolation of LP-sub-Markovian semigroups with Feller semigroups is investigated.
Farkas, Walter, Schilling, René L., Schilling, Rene L, Farkas, Walter; https://orcid.org/, Jacob, Niels   +4 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Solution of fractional differential equations via α−ψ $\alpha-\psi$-Geraghty type mappings

Advances in Difference Equations, 2018
Using fixed point results of α−ψ $\alpha-\psi$-Geraghty contractive type mappings, we examine the existence of solutions for some fractional differential equations in b-metric spaces. By some concrete examples we illustrate the obtained results.
Hojjat Afshari, Sabileh Kalantari, Dumitru Baleanu   +2 more
doaj   +1 more source

Differential and stochastic equations in abstract Wiener space

Journal of Functional Analysis, 1973
AbstractThis paper studies the differential equation (∂∂t) u(t, x) = 12trace A(t, x) D2u(t, x) A∗(t, x) + 〈σ(t, x), Du(t, x)〉 − V(x) u(t, x), u(0, x) = φ(x) in infinite dimensional space. A Kac's type representation of solution in terms of function space integral is proved. Kac's method is modified to work nicely regardless of the dimensionality.
openaire   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Abstract Formulation of the Miura Transform

, 2020
Miura transform is known as the transformation between Korweg de-Vries equation and modified Korweg de-Vries equation. Its formal similarity to the Cole-Hopf transform has been noticed.
Yoritaka Iwata
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

EXISTENCE RESULTS FOR NEUTRAL INTEGRO-DIFFERENTIAL EQUATIONS WITH UNBOUNDED DELAY

, 2011
In this paper we discuss the existence of mild, strict and classical solutions for a class of abstract integro-differential equations in Banach spaces.
SANTOS, Jose Paulo C. Dos, HERNANDEZ, Eduardo, HENRIQUEZ, Hernan   +2 more
core   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source