Results 71 to 80 of about 225,971 (310)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

On the Behaviour of Singular Semigroups in Intermediate and Interpolation Spaces and Its Applications to Maximal Regularity for Degenerate Integro-Differential Evolution Equations

Abstract and Applied Analysis, 2013
For those semigroups, which may have power type singularities and whose generators are abstract multivalued linear operators, we characterize the behaviour with respect to a certain set of intermediate and interpolation spaces.
Alberto Favaron, Angelo Favini
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

A unified theory for continuous-in-time evolving finite element space approximations to partial differential equations in evolving domains [PDF]

, 2017
We develop a unified theory for continuous in time finite element discretisations of partial differential equations posed in evolving domains including the consideration of equations posed on evolving surfaces and bulk domains as well coupled surface ...
C. M. Elliott, T. Ranner
semanticscholar   +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster, Jae Woo Chung, Maria E. Linn‐Evans, Matthew N. Petrucci, Chiahao Lu, Destiny J. Weaver, Joshua De Kam, Scott E. Cooper, Paul J. Tuite, Aleksandar Videnovic, Michael J. Howell, Colum D. MacKinnon   +11 more
wiley   +1 more source

Existence theorem for a unique solution to a coupled system of impulsive fractional differential equations in complex-valued fuzzy metric spaces

Advances in Difference Equations, 2021
In this manuscript, the existence theorem for a unique solution to a coupled system of impulsive fractional differential equations in complex-valued fuzzy metric spaces is studied and the fuzzy version of some fixed point results by using the definition ...
Humaira, Hasanen A. Hammad, Muhammad Sarwar, Manuel De la Sen   +3 more
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Positive Fixed Points for Semipositone Operators in Ordered Banach Spaces and Applications

Abstract and Applied Analysis, 2013
The theory of semipositone integral equations and semipositone ordinary differential equations has been emerging as an important area of investigation in recent years, but the research on semipositone operators in abstract spaces is yet rare.
Zengqin Zhao, Xinsheng Du
doaj   +1 more source

Almost periodic solutions of periodic linear partial functional differential equations

, 2018
We study conditions for the abstract periodic linear functional differential equation $\dot{x}=Ax+F(t)x_t+f(t)$ to have almost periodic with the same structure of frequencies as $f$.
Luong, Vu Trong, Van Minh, Nguyen
core   +1 more source

Bayesian Estimation Improves Prediction of Outcomes After Epilepsy Surgery

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We estimated the statistical power of studies predicting seizure freedom after epilepsy surgery. We extracted data from a Cochrane meta‐analysis. The median power across all studies was 14%. Studies with a median sample size or less (n ≤ 56) and a statistically significant result exaggerated the true effect size by a factor of 5.4, while the ...
Adam S. Dickey, Vineet Reddy, Ammar A. Rashied, Nigel P. Pedersen, Robert T. Krafty   +4 more
wiley   +1 more source