Results 131 to 140 of about 1,466,703 (336)

Environmental conditions dictate differential evolution of vancomycin resistance in Staphylococcus aureus [PDF]

open access: green, 2020
Henrique Machado   +7 more
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Adaptation of the Scaling Factor Based on the Success Rate in Differential Evolution

open access: yesMathematics
Differential evolution is a popular heuristic black-box numerical optimization algorithm which is often used due to its simplicity and efficiency. Parameter adaptation is one of the main directions of study regarding the differential evolution algorithm.
Vladimir Stanovov, Eugene Semenkin
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

An Evolutionary Stacked Ensemble for Improving Accuracy and Computational Efficiency in Daily Photovoltaic Energy Prediction

open access: yesIEEE Access
This study presents a computationally efficient stacked ensemble model for daily photovoltaic energy prediction. The ensemble combines five base regressors: extreme gradient boosting, decision trees, random forests, neural networks, and k-nearest ...
Bilal Rinchi   +4 more
doaj   +1 more source

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