Results 161 to 170 of about 356,284 (355)

Singular fractional evolution differential equations

Open Physics, 2013
Stojanovic Mirjana
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Modern Adaptive Differential Evolution

, 2015
Diplomová práce se zabývá adaptivní verzí diferenciální evoluce s použitím deterministického chaosu pro generování náhodných čísel. Teoretická část obsahuje popis problematiky diferenciální evoluce, adaptivní diferenciální evoluce a popis problematiky ...
Hlaváček, Jiří
core  

Reinforcement learning-controlled differential evolution with L-BFGS refinements. [PDF]

PLoS One
Cao Y, Wu B, Wen M.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Turbo multi-user detection for OFDM/SDMA systems relying on differential evolution aided iterative channel estimation

, 2012
A differential evolution (DE) algorithm aided iterative channel estimation and turbo multi-user detection (MUD) scheme is proposed for multi-user multi-input multiple-output aided orthogonal frequency-division multiplexing/spacedivision multiple-access ...
Chen, Sheng, Mu, Xiaomin, Hanzo, Lajos, Zhang, Jiankang   +3 more
core  

A hybrid fungal growth and differential evolution algorithm for energy-efficient UAV trajectory planning in MEC. [PDF]

Sci Rep
Othman AA, Elmanakhly DA.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hyperparameter optimization of YOLO using differential evolution, multi-fidelity optimization, and Bayesian optimization. [PDF]

Sci Rep
Gill MU, Rajendran P.
europepmc   +1 more source