Results 31 to 40 of about 80,774 (312)

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Optimization of LMBP high-speed railway wheel size prediction algorithm based on improved adaptive differential evolution algorithm

International Journal of Distributed Sensor Networks, 2019
It is beneficial for maintenance department to make maintenance strategy and reduce maintenance cost to forecast the hidden danger index value. Based on the analysis of the research status of wheel-to-life prediction at home and abroad and the repair of ...
Yu Zhang, Jiawen Zhang, Lin Luo, Xiaorong Gao   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

An area coverage algorithm for wireless sensor networks based on differential evolution

International Journal of Distributed Sensor Networks, 2018
Lifetime requirements and coverage demands are emphasized in wireless sensor networks. An area coverage algorithm based on differential evolution is developed in this study to obtain a given coverage ratio ε .
Ning-ning Qin, Jia-le Chen
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Utilizing artificial intelligence to solving time – cost – quality trade-off problem

Scientific Reports, 2022
This study presents the Slime Mold Algorithm (SMA) to solve the time—cost—quality trade-off problem in a construction project. The proposed SMA is a flexible and efficient algorithm in exploration and exploitation to reach the best optimal solution to ...
Pham Vu Hong Son, Luu Ngoc Quynh Khoi
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Automatic reservoir history matching method based on adaptive mutation strategy and differential evolution algorithm

Youqi dizhi yu caishoulu
As a classical evolution algorithm， the differential evolution algorithm has the advantages of global search ability， easy implementation， and no gradient. It has been widely used in automatic reservoir history matching.
ZHANG Jinding, ZHANG Kai, ZHANG Liming, LIU Piyang, CHEN Xu   +4 more
doaj   +1 more source

Quantum Inspired Differential Evolution Algorithm

Open Journal of Optimization, 2015
To enhance the optimization performance of differential evolution algorithm, by studying the implementation mechanism of differential evolution algorithm, a new idea of incorporating differential strategy and rotation of qubits in the Bloch sphere is proposed in this paper.
Binxu Li, Panchi Li
openaire   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source