Results 41 to 50 of about 6,130,994 (293)
FREE SEARCH AND DIFFERENTIAL EVOLUTION TOWARDS DIMENSIONS NUMBER CHANGE [PDF]
, 2006 This paper presents an exploration of Free Search (FS) and modified Differential Evolution (DE) with enhanced adaptivity. The aim of the study is to identify how these methods can cope with changes of the number of variables of a hard design test ...
Penev, Kalin
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Utilizing artificial intelligence to solving time – cost – quality trade-off problem
Scientific Reports, 2022 This study presents the Slime Mold Algorithm (SMA) to solve the time—cost—quality trade-off problem in a construction project. The proposed SMA is a flexible and efficient algorithm in exploration and exploitation to reach the best optimal solution to ...
Pham Vu Hong Son, Luu Ngoc Quynh Khoi
doaj +1 more source
An Adaptive Multiobjective Differential Evolution Algorithm
Journal of Computers, 2013 The mutation strategy and control parameter have a significant influence on the performance of differential evolution. An local and global mutation operator based subregion and external set strategies are proposed in this paper. They use the idea of direct simplex method of mathematical programming.
Fangqing Gu, Hai-Lin Liu 0001
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
A MOS-based Dynamic Memetic Differential Evolution Algorithm for Continuous Optimization: A Scalability Test [PDF]
, 2010 Continuous optimization is one of the areas with more activity in the field of heuristic optimization. Many algorithms have been proposed and compared on several benchmarks of functions, with different performance depending on the problems.
Antonio LaTorre +5 more
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Youqi dizhi yu caishouluAs a classical evolution algorithm， the differential evolution algorithm has the advantages of global search ability， easy implementation， and no gradient. It has been widely used in automatic reservoir history matching.
ZHANG Jinding +4 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Parameter Combination Framework for the Differential Evolution Algorithm [PDF]
Algorithms, 2019 The differential evolution (DE) algorithm is a popular and efficient evolutionary algorithm that can be used for single objective real-parameter optimization. Its performance is greatly affected by its parameters. Generally, parameter control strategies involve determining the most suitable value for the current state; there is only a little research ...
Jinghua Zhang, Ze Dong
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source